ArticleAnatolian journal of cardiology2023
Modified Myocardial Performance Index in Fetal Growth Disturbances as Diagnostic and Prognostic Adjunct.
Article in Anatolian journal of cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Left and right myocardial performance indices in growth-restricted fetuses: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026Pooled it
- Predictive models for adverse pregnancy outcomes in fetal growth restriction: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2026Pooled it
- Myocardial performance index in fetuses with small-for-gestational age in pregnancy: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Intrapartum Fetal Compromise in Late-Onset Fetal Growth Restriction Using the Modified Myocardial Performance Index: A Prospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Observational
- The role of the Mod-MPI in identifying cardiac dysfunction in FGR fetuses stratified by umbilical artery flow abnormalities.BMC pregnancy and childbirth · 2025Observational
- Doppler Evaluation of Fetal Cardiac Function in Gestational Diabetes Mellitus: A Scoping Review Providing Insights into Hemodynamic and Structural Alterations.Journal of clinical medicine · 2025Review
- The Significance of the Myocardial Performance Index and Fetal Doppler Abnormalities in Growth-Restricted Fetuses: A Systematic Review of the Literature.Journal of clinical medicine · 2024Review
- The Relationship Between Fetal Central Nervous System Malformations and Modified Myocardial Performance Index.Cureus · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFetal growth disturbance can be associated with cardiac dysfunction. This study aimed to assess the modified myocardial performance index in growth-restricted and appropriate for gestational age fetuses and evaluate both its prognostic value in perinatal period and also its association with adverse perinatal outcomes.
methodsTotally 131 pregnant women were included in this prospective study. Of these, 56 cases were in study group with a diagnosis of small fetus and 75 cases were in control group with a diagnosis appropriately grown fetus. Fetal echocardiography was performed in all pregnant women to measure modified myocardial performance index. Umbilical, middle cerebral and uterine artery Doppler ultrasound parameters were measured in the study group. Small fetuses were categorized into 2 subgroups of late-onset fetal growth restriction and small for gestational age.
resultsModified myocardial performance index was significantly higher in small fetuses compared to controls (0.45 vs. 0.37, P <.001). Newborn intensive care unit admission rates were significantly higher in small fetuses than in controls (chi-square test, P <.001). The highest mean modified myocardial performance index was recorded in the late-onset fetal growth restriction subgroup (0.45 vs. 0.41 vs. 0.37). The sensitivity and specificity of modified myocardial performance index in predicting adverse outcomes at a cut-off value of 0.41 were 63% and 75%, respectively. There was a significant negative correlation between modified myocardial performance index values and birth weights.
conclusionsWe found higher left fetal heart modified myocardial performance index values in small fetuses indicating the presence of prenatal cardiac dysfunction. Fetal myocardial performance deteriorates in concordance with severity of growth restriction. Modified myocardial performance index can also be used to predict adverse perinatal outcomes among growth-restricted fetuses.
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