Evidence map›Paper›PMID 36680733›Full record

ArticleMolecular neurobiology2023

The Protective Effects of Policosanol on Learning and Memory Impairments in a Male Rat Model of Alzheimer's Disease.

Samaneh Safari, Naser Mirazi, Nesa Ahmadi, Masoumeh Asadbegi, Alireza Nourian, Shahab Ghaderi, Masome Rashno, Alireza Komaki

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Samaneh SafariDepartment of Biology, Faculty of Basic Sciences, Bu-Ali Sina University, Hamedan, Iran.
Naser MiraziDepartment of Biology, Faculty of Basic Sciences, Bu-Ali Sina University, Hamedan, Iran.
Nesa AhmadiDepartment of Biology, Faculty of Basic Sciences, Bu-Ali Sina University, Hamedan, Iran.
Masoumeh AsadbegiDepartment of Neuroscience, School of Science and Advanced Technologies in Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Alireza NourianDepartment of Pathobiology, Faculty of Veterinary Science, Bu-Ali Sina University, Hamedan, Iran.
Shahab GhaderiDepartment of Neuroscience, School of Science and Advanced Technologies in Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Masome RashnoStudent Research Committee, Asadabad School of Medical Sciences, Asadabad, Iran.
Alireza KomakiDepartment of Neuroscience, School of Science and Advanced Technologies in Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. alirezakomaki@gmail.com.ORCID http://orcid.org/0000-0003-3865-9583
Hamedan University of Medical Sciences · IRBu-Ali Sina University · IR

Funding

Bu-Ali Sina University IR.BASU.REC.1399.371
6 · The paper itself

Abstract

Alzheimer's disease (AD), the most common form of dementia, is characterized by a progressive decline in cognitive performance and memory formation. The present study was designed to investigate the effect of policosanol (PCO) on cognitive function, oxidative-antioxidative status, and amyloid-beta (Aβ) plaque formation in an AD rat model induced by intracerebroventricular (ICV) injection of Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAntioxidantsDisease Models, AnimalFatty AlcoholsGum ArabicHippocampusMaleMaze LearningMemory DisordersPeptide FragmentsRatsRats, WistarAmyloid beta-PeptidesAntioxidantsFatty AlcoholsGum ArabicPeptide FragmentspolicosanolAlzheimer’s diseaseOxidative stressPolicosanol, Cognitive declineRat

Identifiers

PMID36680733
OpenAlexW4317636925

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.