Evidence map›Paper›PMID 36685878›Full record

ArticleFrontiers in genetics2022

Incorporating genome-wide and transcriptome-wide association studies to identify genetic elements of longissimus dorsi muscle in Huaxi cattle.

Mang Liang, Bingxing An, Tianyu Deng, Lili Du, Keanning Li, Sheng Cao, Yueying Du, Lingyang Xu, Lupei Zhang, Xue Gao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Mang LiangInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Bingxing AnInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Tianyu DengInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Lili DuInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Keanning LiInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Sheng CaoInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Yueying DuInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Lingyang XuInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Lupei ZhangInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Xue GaoInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Yang CaoJilin Academy of Agricultural Sciences, Changchun, China.
Yuming ZhaoJilin Academy of Agricultural Sciences, Changchun, China.
Junya LiInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Huijiang GaoInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Animal Science Research Institute · CNChinese Academy of Agricultural Sciences · CNJilin Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Locating the genetic variation of important livestock and poultry economic traits is essential for genetic improvement in breeding programs. Identifying the candidate genes for the productive ability of Huaxi cattle was one crucial element for practical breeding. Based on the genotype and phenotype data of 1,478 individuals and the RNA-seq data of 120 individuals contained in 1,478 individuals, we implemented genome-wide association studies (GWAS), transcriptome-wide association studies (TWAS), and Fisher's combined test (FCT) to identify the candidate genes for the carcass trait, the weight of longissimus dorsi muscle (LDM). The results indicated that GWAS, TWAS, and FCT identified seven candidate genes for LDM altogether:

Indexed as

FCTGWASHuaxi cattlelongissimus dorsi muscleTWAS

Identifiers

PMID36685878
PMCPMC9852892
OpenAlexW4313595557

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.