ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2023
Epinephrine iontophoresis attenuates changes in skin blood flow and abolishes cutaneous contamination of near-infrared diffuse correlation spectroscopy estimations of muscle perfusion.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 7 citations in OpenAlex.
- Pressure-dependent coupling between arterial pressure and intercostal muscle blood-flow index during acute hypotension in humans.Experimental physiology · 2026Article
- DCS blood flow index underestimates skeletal muscle perfusionJournal of biomedical optics · 2024Article
- Deep-learning-based separation of shallow and deep layer blood flow rates in diffuse correlation spectroscopy.Biomedical optics express · 2023Article
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8 authors at 2 institutions in 1 country.
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Abstract
Near-infrared diffuse correlation spectroscopy (NIR-DCS) is an optical imaging technique for measuring relative changes in skeletal muscle microvascular perfusion (i.e., fold change above baseline) during reactive hyperemia testing and exercise and is reported as a blood flow index (BFI). Although it is generally accepted that changes in BFI are primarily driven by changes in muscle perfusion, it is well known that large, hyperthermia-induced changes in cutaneous blood flow can uncouple this relationship. What remains unknown, is how much of an impact that changes in cutaneous perfusion have on NIR-DCS BFI and estimates of skeletal muscle perfusion under thermoneutral conditions, where changes in cutaneous blood flow are assumed to be relatively low. We therefore used epinephrine iontophoresis to pharmacologically block changes in cutaneous perfusion throughout a battery of experimental procedures. The data show that
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