Evidence map›Paper›PMID 36696106›Full record

ArticleEnvironmental health perspectives2023

Exposure to Air Pollution during Pre-Hypertension and Subsequent Hypertension, Cardiovascular Disease, and Death: A Trajectory Analysis of the UK Biobank Cohort.

Shiyu Zhang, Zhengmin Min Qian, Lan Chen, Xing Zhao, Miao Cai, Chongjian Wang, Hongtao Zou, Yinglin Wu, Zilong Zhang, Haitao Li and 1 more

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 63 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 3 pooled it
19.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 122 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Ambient PMEnvironment & health (Washington, D.C.) · 2026
    Article
  9. Article
  10. PMAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Ambient Air Pollution and COVID-19 in California.Research report (Health Effects Institute) · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Shiyu ZhangDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Zhengmin Min QianDepartment of Epidemiology and Biostatistics, College for Public Health and Social Justice, Saint Louis University, Saint Louis, Missouri, USA.
Lan ChenDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-8775-4301
Xing ZhaoWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China.
Miao CaiDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Chongjian WangDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Hongtao ZouDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Yinglin WuDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Zilong ZhangDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Haitao LiShenzhen University General Hospital, Shenzhen University Clinical Medical Academy, Shenzhen, China.
Hualiang LinDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-3643-9408
Sun Yat-sen University · CNSaint Louis University · USShenzhen University · CNSichuan University · CNZhengzhou University · CN

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

backgroundThe associations between air pollution exposure and morbidity and mortality of cardiovascular diseases (CVDs) have been widely reported; however, evidence on such associations across different dynamic disease trajectories remain unknown.

objectiveWe examined whether ambient air pollution during the prehypertension (pre-HTN) stage could aggravate the progression from hypertension (HTN) to CVD, and consequent death.

methodsA total of 168,010 adults with pre-HTN (

resultsDuring a median follow-up of 12 y, 13,743 (8.18%) of participants with pre-HTN developed HTN, whereas 12,825 (7.63%) and 4,467 (2.66%) directly developed CVD or died, respectively. Air pollution was positively associated with the dynamic disease progression. For example, a per-interquartile range increase of

conclusionsThis study provides evidence that air pollution might play a role in the early stages of CVD progression. Controlling air pollution might be an effective measure to prevent CVD progression and reduce the disease burden of CVD. https://doi.org/10.1289/EHP10967.

Indexed as

Air PollutantsAir PollutionCardiovascular DiseasesHypertensionPrehypertensionAdultBiological Specimen BanksDisease ProgressionEnvironmental ExposureHumansParticulate MatterUnited KingdomAir PollutantsParticulate Matter

Identifiers

PMID36696106
PMCPMC9875843
OpenAlexW4317951395

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.