ArticleCommunications chemistry2022
Quasi-continuous production of highly hyperpolarized carbon-13 contrast agents every 15 seconds within an MRI system.
Article in Communications chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Minute-Scale Repeated Metabolic Probing of Living Cells Enabled by Rapid Parahydrogen-Based Hyperpolarization.Angewandte Chemie (International ed. in English) · 2026Article
- Intermolecular Nuclear Spin Hyperpolarization Transfer via Cross-Relaxation Triggers RASER of Solute Molecules.Angewandte Chemie (International ed. in English) · 2026Article
- Upscaling the Hyperpolarization Sample Volume of an Automated Hydrogenative Parahydrogen-Induced Polarizer.ACS measurement science au · 2025Article
- Novel non‑metal‑based contrast agents for MR imaging: Emerging approaches and clinical perspectives (Review).International journal of oncology · 2025Review
- Overcoming the Challenges of Hyperpolarizing Substrates with Parahydrogen-Induced Polarization in an MRI System.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Homogeneous Catalysts for Hydrogenative PHIP Used in Biomedical Applications.Analysis & sensing · 2025Article
- Yeast Solutions and Hyperpolarization Enable Real-Time Observation of Metabolized Substrates Even at Natural Abundance.Analytical chemistry · 2024Article
- Rapid in situ carbon-13 hyperpolarization and imaging of acetate and pyruvate esters without external polarizer.Communications chemistry · 2024Article
- New Horizons in HyperpolarizedMolecular imaging and biology · 2024Article
- Spying on parahydrogen-induced polarization transfer using a half-tesla benchtop MRI and hyperpolarized imaging enabled by automation.Nature communications · 2023Article
- Metabolic Tumor Imaging with Rapidly Signal-Enhanced 1-Chemphyschem : a European journal of chemical physics and physical chemistry · 2023Article
- Catalyst-Free Aqueous Hyperpolarized [1-ACS sensors · 2022Article
- Parahydrogen-induced polarization and spin order transfer in ethyl pyruvate at high magnetic fields.Scientific reports · 2022Article
- Through-Space Multinuclear Magnetic Resonance Signal Enhancement Induced by Parahydrogen and Radiofrequency Amplification by Stimulated Emission of Radiation.Analytical chemistry · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Hyperpolarized contrast agents (HyCAs) have enabled unprecedented magnetic resonance imaging (MRI) of metabolism and pH in vivo. Producing HyCAs with currently available methods, however, is typically time and cost intensive. Here, we show virtually-continuous production of HyCAs using parahydrogen-induced polarization (PHIP), without stand-alone polarizer, but using a system integrated in an MRI instead. Polarization of ≈2% for [1-
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.