ReviewFrontiers in bioengineering and biotechnology2022
Biological properties and surgical applications of the human amniotic membrane.
Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Utilization of human amniotic membrane (HAM) in tympanoplasty: a systematic review and meta-analysis.Cell and tissue banking · 2026Pooled it
- Pooled it
- Activities of human amniotic membrane extracellular vesicles with a focus on ophthalmology.Molecular biology reports · 2026Review
- Enhanced decellularization of human amniotic membrane: optimizing dna clearance and protein retention for clinical applications.Molecular biology reports · 2026Article
- Intraoperative Agents for Hemostasis and Dural Reconstruction in Neurosurgery.Neurosurgery practice · 2026Review
- Minimal immune response after transplantation of a cryopreserved human amniotic membrane on the ocular surface.Materials today. Bio · 2026Article
- Nur77 Regulates the Phosphorylation of Smad3, Thereby Influencing Skeletal Muscle Fibrosis Caused by Obesity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Experimental esophageal reconstruction in dogs using autologous platelet-rich plasma-augmented acellular amniotic membrane scaffold.Open veterinary journal · 2026Article
- The use of human decellularized amniotic membrane as pulmonary valve leaflets in right ventricular outflow tract reconstruction - anFrontiers in bioengineering and biotechnology · 2026Article
- Human Amniotic Membrane Procurement Protocol and Evaluation of a Simplified Alkaline Decellularization Method.Methods and protocols · 2026Article
- Reassessing the cryopreserved human amniotic membrane's low immunogenicity due to advances in histocompatibility.Materials today. Bio · 2025Article
- Advanced analysis of nonlinear stability of two horizontal interfaces separating three-stratified non-Newtonian liquids.Scientific reports · 2025Article
- Three-dimensionally decellularized human amniotic membrane scaffold: structure, processing, and biological properties.Cell and tissue banking · 2025Article
- Air-Dried Human Amniotic Membranes: Sterility, Microbial Barrier, and Cytokine Retention.Cureus · 2025Article
- Outcomes of Regenerative Endodontic Therapy Using Dehydrated Human-Derived Amnion-Chorion Membranes and Collagen Matrices: A Retrospective Analysis.Biomimetics (Basel, Switzerland) · 2025Article
- Remarkable healing of a severe wound through surgical debridement, honey medicinal application, amniotic membrane, and bovine collagen powder; A case report study.International journal of surgery case reports · 2025Article
- Comparing Amniotic Membranes to Other Bioengineered Skin Substitutes in Wound Healing: A Propensity Score-Matched Analysis.Journal of clinical medicine · 2025Article
- Efficacy of xenogeneic fresh and lyophilized amniotic membranes on the healing of experimentally induced full-thickness skin wounds in dogs.Scientific reports · 2025Article
- Elevating Dermatology Beyond Aesthetics: Perinatal-Derived Advancements for Rejuvenation, Alopecia Strategies, Scar Therapies, and Progressive Wound Healing.Stem cell reviews and reports · 2025Review
- Perspectives on the use of decellularized/devitalized and lyophilized human perinatal tissues for bone repair: Advantages and remaining challenges.Materials today. Bio · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The amniotic membrane (AM) is the inner part of the placenta. It has been used therapeutically for the last century. The biological proprieties of AM include immunomodulatory, anti-scarring, anti-microbial, pro or anti-angiogenic (surface dependent), and tissue growth promotion. Because of these, AM is a functional tissue for the treatment of different pathologies. The AM is today part of the treatment for various conditions such as wounds, ulcers, burns, adhesions, and skin injury, among others, with surgical resolution. This review focuses on the current surgical areas, including gynecology, plastic surgery, gastrointestinal, traumatology, neurosurgery, and ophthalmology, among others, that use AM as a therapeutic option to increase the success rate of surgical procedures. Currently there are articles describing the mechanisms of action of AM, some therapeutic implications and the use in surgeries of specific surgical areas, this prevents knowing the therapeutic response of AM when used in surgeries of different organs or tissues. Therefore, we described the use of AM in various surgical specialties along with the mechanisms of action, helping to improve the understanding of the therapeutic targets and achieving an adequate perspective of the surgical utility of AM with a particular emphasis on regenerative medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.