Evidence map›Paper›PMID 36699010›Full record

ArticleFrontiers in cell and developmental biology2022

Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development.

Neophytos Christodoulou, Paris A Skourides

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. The Role of Glucose Metabolism inInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. The Mechanics of Building Functional Organs.Cold Spring Harbor perspectives in biology · 2025
    Review
  6. Article
  7. A computational dynamic systems model forCurrent research in toxicology · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Neophytos ChristodoulouDepartment of Biological Sciences, University of Cyprus, Nicosia, Cyprus.
Paris A SkouridesDepartment of Biological Sciences, University of Cyprus, Nicosia, Cyprus.
University of Cyprus · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects. While the intrinsic morphogenetic events shaping the neuroepithelium have been studied extensively, how tissues mechanically coupled with the neural plate influence neural tube closure remains poorly understood. Here, using

Indexed as

apical constrictionembryogenesisneural tube closureneural tube defectsXenopus

Identifiers

PMID36699010
PMCPMC9868421
OpenAlexW4313826374

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.