Evidence map›Paper›PMID 36703960›Full record

ArticleFrontiers in immunology2022

Three doses of BNT162b2 COVID-19 mRNA vaccine establish long-lasting CD8

Susana Patricia Amaya Hernandez, Ditte Stampe Hersby, Kamilla Kjærgaard Munk, Tripti Tamhane, Darya Trubach, Maria Tagliamonte, Luigi Buonaguro, Anne Ortved Gang, Sine Reker Hadrup, Sunil Kumar Saini

Abstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. mRNA vaccines as cancer therapies.Chinese medical journal · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Susana Patricia Amaya HernandezDepartment of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.
Ditte Stampe HersbyDepartment of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Kamilla Kjærgaard MunkDepartment of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.
Tripti TamhaneDepartment of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.
Darya TrubachDepartment of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.
Maria TagliamonteInnovative Immunological Models Unit, National Cancer Institute Pascale Foundation - IRCCS, Napoli, Italy.
Luigi BuonaguroInnovative Immunological Models Unit, National Cancer Institute Pascale Foundation - IRCCS, Napoli, Italy.
Anne Ortved GangDepartment of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Sine Reker HadrupDepartment of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.
Sunil Kumar SainiDepartment of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with hematological malignancies are prioritized for COVID-19 vaccine due to their high risk for severe SARS-CoV-2 infection-related disease and mortality. To understand T cell immunity, its long-term persistence, and its correlation with antibody response, we evaluated the BNT162b2 COVID-19 mRNA vaccine-specific immune response in chronic lymphocytic leukemia (CLL) and myeloid dysplastic syndrome (MDS) patients. Longitudinal analysis of CD8

Indexed as

BNT162 VaccineCOVID-19Leukemia, Lymphocytic, Chronic, B-CellMyelodysplastic SyndromesCD8-Positive T-LymphocytesHumansSARS-CoV-2BNT162 VaccineCD8+ T cellHematological cancermRNA vaccine against SARS-CoV-2SARS – CoV – 2T-cell immunityT cell memory

Identifiers

PMID36703960
PMCPMC9873231

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.