Evidence map›Paper›PMID 36707339›Full record

ReviewTrends in immunology2023

Harnessing prostaglandin E

Juliann B Burkett, Amanda C Doran, Maureen Gannon

Open access · greenAbstract readReview
In one paragraph

Review in Trends in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Metagenomic Insights into Gut Microbiota Alterations FollowingInternational journal of molecular sciences · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. 15-PGDH inhibition preserves blood-brain barrier integrity and cognition.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Metabolic reprogramming in efferocytosis.Frontiers in cell and developmental biology · 2025
    Review
  19. Article
  20. mCell metabolism · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Juliann B BurkettDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Amanda C DoranDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Maureen GannonDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA; Department of Veterans Affairs Tennessee Valley, Nashville, TN, USA. Electronic address: maureen.gannon@vumc.org.
Vanderbilt University · USVanderbilt University Medical Center · US

Funding

MULTIDISCIPLINARY TRAINING IN MOLECULAR ENDOCRINOLOGYT32DK007563 · NIDDK · VANDERBILT UNIVERSITY · PI Richard M O'Brien · 1988 to 2026
$15.9M
Critical Mediators of Inflammation Resolution and Immune Memory in AtherosclerosisR01HL159487 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DORAN, AMANDA C · 2021 to 2025
$3.2M
Manipulating islet GPCR activity to promote beta cell proliferation and survivalR01DK120626 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GANNON, MAUREEN A · 2019 to 2022
$1.7M
Modulating prostaglandin E2 receptor activity to improve pancreatic islet functionI01BX005399 · VA · VETERANS HEALTH ADMINISTRATION · PI GANNON, MAUREEN A · 2022 to 2025
–
BLRD VA I01 BX005399NHLBI NIH HHS R01 HL159487NIDDK NIH HHS R01 DK120626NIDDK NIH HHS T32 DK007563
6 · The paper itself

Abstract

The etiology of most autoimmune diseases remains unknown; however, shared among them is a disruption of immunoregulation. Prostaglandin lipid signaling molecules possess context-dependent immunoregulatory properties, making their role in autoimmunity difficult to decipher. For example, prostaglandin E

Indexed as

Autoimmune DiseasesAutoimmunityDinoprostoneHumansSignal TransductionT-Lymphocyte SubsetsDinoprostoneanti-inflammatoryinflammationmacrophagePGE(2)proinflammatoryT cells

Identifiers

PMID36707339
PMCPMC9975049
OpenAlexW4318019502

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.