Evidence map›Paper›PMID 36710351›Full record

ArticleJournal of neuroinflammation2023

Nanoparticulate MgH

Zhenghao Li, Kefu Chen, Qi Shao, Hongtao Lu, Xin Zhang, Yingyan Pu, Xuejun Sun, Hua He, Li Cao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroinflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

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  13. Nanoparticulate MgHMolecular pain
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhenghao Li *Institute of Neuroscience and Key Laboratory of Molecular Neurobiology of Military of Education, Naval Medical University, Shanghai, 200433, China.
Kefu Chen *Institute of Neuroscience and Key Laboratory of Molecular Neurobiology of Military of Education, Naval Medical University, Shanghai, 200433, China.
Qi Shao *Institute of Neuroscience and Key Laboratory of Molecular Neurobiology of Military of Education, Naval Medical University, Shanghai, 200433, China.
Hongtao Lu *Department of Naval Medicine, Naval Medical University, Shanghai, 200433, China.
Xin ZhangInstitute of Neuroscience and Key Laboratory of Molecular Neurobiology of Military of Education, Naval Medical University, Shanghai, 200433, China.
Yingyan PuInstitute of Neuroscience and Key Laboratory of Molecular Neurobiology of Military of Education, Naval Medical University, Shanghai, 200433, China.
Xuejun SunDepartment of Naval Medicine, Naval Medical University, Shanghai, 200433, China.
Hua HeDepartment of Neurosurgery, Third Affiliated Hospital, Naval Medical University, Shanghai, 200438, China. hehua1624@smmu.edu.cn.
Li CaoInstitute of Neuroscience and Key Laboratory of Molecular Neurobiology of Military of Education, Naval Medical University, Shanghai, 200433, China. caoli@smmu.edu.cn.
Second Military Medical University · CNNaval University of Engineering · CN

Funding

Foundation of Center of Hydrogen Science WF510105001Foundation of Naval Medical University 2019QH001National Natural Science Foundation of China 31771129National Natural Science Foundation of China 31871026National Natural Science Foundation of China 32100935Postdoctoral Research Foundation of China 2019M663982
6 · The paper itself

Abstract

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). Anxiety and depression are the most common psychiatric comorbidities of MS, which seriously affect patients' quality of life, treatment compliance, and prognosis. However, current treatments for anxiety and depression in MS show low therapeutic efficacy and significant side effects. In the present study, we explored the therapeutic effects of a novel low-toxic anti-inflammatory drug, nanoparticulate magnesium hydride (MgH

Indexed as

Encephalomyelitis, Autoimmune, ExperimentalMultiple SclerosisAnimalsAnxietyDepressionMiceMice, Inbred C57BLMicrogliaOxidative StressQuality of LifeAnxietyDepressionEAEMgH2Microglial polarizationMultiple sclerosisNeuroinflammation

Identifiers

PMID36710351
PMCPMC9885636
OpenAlexW4318457243

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.