Evidence map›Paper›PMID 36710880›Full record

ArticleFrontiers in molecular biosciences2022

Innate immunity mediator STING modulates nascent DNA metabolism at stalled forks in human cells.

Pavlo Lazarchuk, Vy N Nguyen, Salomé Brunon, Maria N Pavlova, Julia M Sidorova

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. STING causes replication stress and nascent DNA degradation via SAMHD1.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. A noncanonical cGAS-STING pathway drives cellular and organismal aging.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pavlo LazarchukDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, United States.
Vy N NguyenDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, United States.
Salomé BrunonDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, United States.
Maria N PavlovaDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, United States.
Julia M SidorovaDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, United States.
University of Washington · US

Funding

Epigenetics of replication stress in human cellsR01GM115482 · NIGMS · UNIVERSITY OF WASHINGTON · PI SIDOROVA, JULIA · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM115482
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

humanhydroxyureainnate immunitynascent DNAreplicationSTING

Identifiers

PMID36710880
PMCPMC9877313
OpenAlexW4315782213

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.