Evidence map›Paper›PMID 36711464›Full record

ArticlebioRxiv : the preprint server for biology2023

Developmental hearing loss-induced perceptual deficits are rescued by cortical expression of GABA

Samer Masri, Regan Fair, Todd M Mowery, Dan H Sanes

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Samer MasriCenter for Neural Science, New York University, 4 Washington Place, New York, NY 10003.
Regan FairCenter for Neural Science, New York University, 4 Washington Place, New York, NY 10003.
Todd M MoweryBrain Health Institute & Department of Otolaryngology, Rutgers University.
Dan H SanesCenter for Neural Science, New York University, 4 Washington Place, New York, NY 10003.
New York University · USNYU Langone Health · USRutgers, The State University of New Jersey · US

Funding

Rescue of cortical inhibitory synapses following developmental hearing lossR01DC011284 · NIDCD · NEW YORK UNIVERSITY · PI SANES, DAN HARVEY · 2011 to 2022
$5.4M
Genetic rescue of a developmental hearing loss-induced spectral processing deficitF32DC020659 · NIDCD · NEW YORK UNIVERSITY · PI MASRI, SAMER · 2022 to 2024
$218k
NIDCD NIH HHS F32 DC020659NIDCD NIH HHS R01 DC011284
6 · The paper itself

Abstract

Even transient periods of developmental hearing loss during the developmental critical period have been linked to long-lasting deficits in auditory perception, including temporal and spectral processing, which correlate with speech perception and educational attainment. In gerbils, hearing loss-induced perceptual deficits are correlated with a reduction of both ionotropic GABA

Indexed as

auditory cortexauditory perceptionGABAAGABABhearing losssynaptic inhibition

Identifiers

PMID36711464
PMCPMC9882079
OpenAlexW4315471086

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.