Evidence map›Paper›PMID 36711745›Full record

ArticlebioRxiv : the preprint server for biology2023

Molecular Logic of Synaptic Diversity Between

Suresh K Jetti, Andrés B Crane, Yulia Akbergenova, Nicole A Aponte-Santiago, Karen L Cunningham, Charles A Whittaker, J Troy Littleton

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Suresh K JettiThe Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139.
Andrés B CraneThe Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139.
Yulia AkbergenovaThe Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139.
Nicole A Aponte-SantiagoThe Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139.
Karen L CunninghamThe Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139.
Charles A WhittakerKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139.
J Troy LittletonThe Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139.

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Cale Whitworth · 2014 to 2026
$13.5M
Imaging Synaptic Transmission of Individual Active ZonesR01MH104536 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI J. TROY LITTLETON · 2014 to 2026
$4.7M
Molecular and Cellular Mechanisms Mediating Structural and Functional Active Zone MaturationR01NS117588 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LITTLETON, J. TROY · 2021 to 2025
$1.9M
Effect of Nanoscale Active Zone Morphology on Synaptic Vesicle Release ProbabilityF31NS118948 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CRANE, ANDRES · 2020 to 2022
$103k
NIGMS NIH HHS T32 GM007287NIH HHS P40 OD018537NIMH NIH HHS R01 MH104536NINDS NIH HHS F31 NS118948NINDS NIH HHS R01 NS117588
6 · The paper itself

Abstract

Although neuronal subtypes display unique synaptic organization and function, the underlying transcriptional differences that establish these features is poorly understood. To identify molecular pathways that contribute to synaptic diversity, single neuron PatchSeq RNA profiling was performed on

Identifiers

PMID36711745
PMCPMC9882338

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.