Evidence map›Paper›PMID 36711888›Full record

ArticleResearch square2024

Migrate3D: Software for simplified post-tracking analysis of 3D and 2D cell migration data.

Emily R Mynar, Matthew W Kinahan, Markus Thali, Menelaos Symeonides

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emily R MynarUniversity of Vermont.
Matthew W KinahanUniversity of Vermont.
Markus ThaliUniversity of Vermont.ORCID 0000-0001-8621-2095
Menelaos SymeonidesUniversity of Vermont.ORCID 0000-0003-3476-9881

Funding

Multiscale analysis of HIV-1-induced small T cell syncytiaR01AI172486 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Markus Thali · 2023 to 2026
$2.2M
Multiscale analysis of HIV-1-induced small T cell syncytiaR56AI172486 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI THALI, MARKUS · 2022 to 2022
$596k
The Host Response Against HIV-1-induced T Cell SyncytiaR21AI152816 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI THALI, MARKUS · 2020 to 2021
$429k
NIAID NIH HHS R01 AI172486NIAID NIH HHS R21 AI152816NIAID NIH HHS R56 AI172486
6 · The paper itself

Abstract

Migrate3D is a cell migration analysis tool whose purpose is to computationally process positional cell tracking data generated via other image acquisition/analysis software and generate biologically meaningful results. The functionalities of Migrate3D include step-based calculations of each cell track, single-cell-level summary statistics, mean squared displacement analysis, and machine learning-based evaluation of the entire dataset and subpopulations of cells found within it. The parameters calculated within Migrate3D have been previously developed and validated by other groups, and were selected to facilitate extraction of the maximum depth of information possible from input datasets. Variables are user-adjustable to enable customized analyses of diverse motility patterns and cell types, both in three-and two-dimensional timelapse data. Independent of any particular upstream image analysis or cell tracking software, Migrate3D only needs positional data over time to execute the suite of calculations. This presents a unique opportunity to standardize and streamline cell migration analysis.

Indexed as

bioinformaticscell biologycell migrationcell motilitymachine learningprincipal component analysispythonquantitative biology

Identifiers

PMID36711888
PMCPMC9882690

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.