ArticleFrontiers in endocrinology2022
Multiple statistical models reveal specific volatile organic compounds affect sex hormones in American adult male: NHANES 2013-2016.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Congener-Specific Associations of Per- and Polyfluoroalkyl Substances With Obesity-Metabolic Phenotypes: A Multimodel Analysis.Obesity (Silver Spring, Md.) · 2026Article
- An Exploration of Machine Learning Methods in Human Biomonitoring.International journal of environmental research and public health · 2026Review
- Association between ethylene oxide exposure and serum sex hormone in adult males: the mediating role of serum albumin.Hormones (Athens, Greece) · 2026Article
- Closing the Exposure Dimension Gap in Chronic Disease Prevention: Evidence from Per- and Polyfluoroalkyl Substances and the Global Burden of Diabetic Kidney Disease.Health data science · 2026Article
- Internal Exposure to BTEX in Tropical Children: Does Exposure Speed Up Pubertal Development?Antioxidants (Basel, Switzerland) · 2025Article
- Ferroptosis induced by environmental pollutants and its health implications.Cell death discovery · 2025Review
- Inflammatory markers partially mediate the association between volatile organic compounds exposure and hyperlipidemia: a nationally representative cross-sectional study from NHANES.Frontiers in public health · 2025Article
- Association between volatile organic compounds exposure and infertility risk among American women aged 18-45 years from NHANES 2013-2020.Scientific reports · 2024Article
- Identifying effects of volatile organic compounds exposure on kidney stone prevalence in U.S. adults: a cross-sectional analysis of NHANES 2007-2020.BMC public health · 2024Article
- Association between Healthy Eating Index-2015 total and component food scores with reproductive lifespan among postmenopausal women: a population-based study from NHANES 2005-2016.BMC public health · 2024Article
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- Associations of urinary caffeine metabolites with sex hormones: comparison of three statistical models.Frontiers in nutrition · 2024Article
- Associations of exposure to volatile organic compounds with sleep health and potential mediators: analysis of NHANES data.Frontiers in public health · 2024Article
- The exposure to volatile organic compounds associate positively with overactive bladder risk in U.S. adults: a cross-sectional study of 2007-2020 NHANES.Frontiers in public health · 2024Article
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Corrections and comments
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Authors and funding
15 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Some VOCs are identified as endocrine-disrupting chemicals (EDCs), interfering with the effect of sex hormones. However, no studies focused on the common spectrum of environmental VOCs exposure affecting sex hormones in the average male population. Objectives: We aimed to explore the association between VOCs and sex hormones in American adult males using multiple statistical models. Methods: The generalized linear (GLM), eXtreme Gradient Boosting (XGBoost), weighted quantile sum (WQS), Bayesian kernel machine regression (BKMR) and stratified models were used to evaluate the associations between Specific Volatile Organic Compounds and sex hormones in American adult male from NHANES 2013-2016. Results: Pearson correlation model revealed the potential co-exposure pattern among VOCs. XGBoost algorithm models and the WQS model suggested the relative importance of VOCs. BKMR models reveal that co-exposure to the VOCs was associated with increased Testosterone (TT), Estradiol (E Conclusion: This study is an academic illustration of the association between VOCs exposure and sex hormones, suggesting that exposure to VOCs might be associated with sex hormone metabolic disorder in American adult males.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.