Evidence map›Paper›PMID 36718322›Full record

ArticleVeterinary world2022

Toxicity test of flavonoid compounds from the leaves of

Mochamad Lazuardi, Suharjono Suharjono, Chi-Hsien Chien, Jie-Long He, Chi-Wen Lee, Chia-Kang Peng, Mohammad Sukmanadi, Rahmi Sugihartuti, Lilik Maslachah

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Mochamad LazuardiSub-division Veterinary-Pharmacy, Faculty of Veterinary Medicine, Universitas Airlangga, Mulyorejo Road, 60115, Surabaya, Indonesia.
Suharjono SuharjonoDepartment of Pharmaceutics, Faculty of Pharmacy, Universitas Airlangga, Mulyorejo Road, 60115, Surabaya, Indonesia.
Chi-Hsien ChienDepartment of Veterinary Medicine, Asia University, No. 500, Lioufeng Road, Wufeng District, Taichung 41354, Taiwan.
Jie-Long HeDepartment of Veterinary Medicine, Asia University, No. 500, Lioufeng Road, Wufeng District, Taichung 41354, Taiwan.
Chi-Wen LeeDepartment of Veterinary Medicine, Asia University, No. 500, Lioufeng Road, Wufeng District, Taichung 41354, Taiwan.
Chia-Kang PengDepartment of Veterinary Medicine, Asia University, No. 500, Lioufeng Road, Wufeng District, Taichung 41354, Taiwan.
Mohammad SukmanadiSub-division Veterinary-Pharmacy, Faculty of Veterinary Medicine, Universitas Airlangga, Mulyorejo Road, 60115, Surabaya, Indonesia.
Rahmi SugihartutiSub-division Veterinary-Pharmacy, Faculty of Veterinary Medicine, Universitas Airlangga, Mulyorejo Road, 60115, Surabaya, Indonesia.
Lilik MaslachahSub-division Veterinary-Pharmacy, Faculty of Veterinary Medicine, Universitas Airlangga, Mulyorejo Road, 60115, Surabaya, Indonesia.
Airlangga University · IDAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: The flavonoids from mistletoe are thought to have antimicrobial action. This encouraging finding supports the benefits of medicinal plants as a substitute for synthetic antimicrobials, thus promoting healthy lifestyles. In contrast, it is known that the use of topical drug formulations made from flavonoids of mistletoe ( Materials and Methods: A myeloma cell line was cultured in Roswell Park Memorial Institute medium, and the Baby Hamster Kidney clone 12 (BHK Results: Cytopathic effect was detected on the microtiter plate wells for the groups of myeloma and BHK Conclusion: Flavonoid compounds from BD were safely used for topical treatment of cancer cells at a concentration <2.491 μg/mL, whereas for non-cancerous cells, a concentration <2.582 μg/mL was sufficient (p < 0.05).

Indexed as

antimicrobialBaby Hamster Kidney clone 12 cell culturecytopathic effecthealthy lifestylemyeloma cell culture

Identifiers

PMID36718322
PMCPMC9880835
OpenAlexW4312043189

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.