Evidence map›Paper›PMID 36719192›Full record

ArticlemBio2023

Adeno-Associated Virus Monoinfection Induces a DNA Damage Response and DNA Repair That Contributes to Viral DNA Replication.

Kang Ning, Cagla Aksu Kuz, Fang Cheng, Zehua Feng, Ziying Yan, Jianming Qiu

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kang NingDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Cagla Aksu KuzDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Fang ChengDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Zehua FengDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, USA.
Ziying YanDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, USA.
Jianming QiuDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0000-0001-9850-1695
University of Kansas Medical Center · USUniversity of Iowa · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
Viral and Host Determinants of Parvovirus ReplicationR01AI150877 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2020 to 2024
$2.4M
Super resolution microscope for the imaging core facilityS10OD023625 · OD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NISHIMUNE, HIROSHI · 2019 to 2019
$987k
Development of a Novel rAAV Vector Without Cross-species Barrier to Transduce Human and Ferret Conducting AirwaysR21AI156448 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING, YAN, ZIYING · 2021 to 2022
$438k
NIAID NIH HHS R01 AI150877NIAID NIH HHS R21 AI156448NIDDK NIH HHS P30 DK054759NIH HHS S10 OD023625
6 · The paper itself

Abstract

Adeno-associated virus (AAV) belongs to the

Indexed as

HistonesVirus ReplicationDependovirusDNA DamageDNA RepairDNA ReplicationDNA, ViralGenetic VectorsHEK293 CellsHumansDNA, ViralHistonesAAVadeno-associated virusDDRDNA damage responseDNA repairDNA replicationmonoinfection

Identifiers

PMID36719192
PMCPMC9973366
OpenAlexW4318620434

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.