Evidence map›Paper›PMID 36720389›Full record

ArticleThe journal of allergy and clinical immunology. In practice2023

Assessing Disparities in the Prevalence of Atopic Comorbidities Among Food-Allergic Children.

Anandu Dileep, Christopher Warren, Lucy A Bilaver, Ellen Stephen, Aame B Andy-Nweye, Susan Fox, Jialing Jiang, Pamela J Newmark, Annika Chura, Iman Abdikarim and 6 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Total Serum IgE in a Cohort of Children With Food Allergy.The journal of allergy and clinical immunology. In practice · 2025
    Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Anandu DileepDivision of Allergy and Immunology, Rush University Medical Center, Chicago, Ill.
Christopher WarrenDivision of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Allergy and Immunology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill.
Lucy A BilaverDivision of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Ellen StephenDivision of Allergy and Immunology, Rush University Medical Center, Chicago, Ill.
Aame B Andy-NweyeDivision of Allergy and Immunology, Rush University Medical Center, Chicago, Ill.
Susan FoxDivision of Allergy and Immunology, Rush University Medical Center, Chicago, Ill.
Jialing JiangDivision of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Pamela J NewmarkDivision of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Annika ChuraDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Iman AbdikarimDivision of Allergy and Immunology, Children's National Health Systems, Washington DC.
Sai R NimmagaddaDivision of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Allergy and Immunology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill.
Hemant P SharmaDivision of Allergy and Immunology, Children's National Health Systems, Washington DC.
Mary C TobinDivision of Allergy and Immunology, Rush University Medical Center, Chicago, Ill.
Amal H Assa'adDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Ruchi S GuptaDivision of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Allergy and Immunology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill.
Mahboobeh MahdaviniaDivision of Allergy and Immunology, Rush University Medical Center, Chicago, Ill. Electronic address: mahboobeh_mahdavinia@rush.edu.
Rush University Medical Center · USNorthwestern University · USChildren's National · USCincinnati Children's Hospital Medical Center · USLurie Children's Hospital · USLurie Children's Hospital · US

Funding

FORWARD Supplement Standardizing EHR Data CollectionR01AI130348 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Ruchi S Gupta · 2017 to 2026
$10.9M
Cognitive Impairment in Chronic RhinosinusitisR03TR004005 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MAHDAVINIA, MAHBOOBEH · 2022 to 2023
$158k
NCATS NIH HHS R03 TR004005NIAID NIH HHS R01 AI130348
6 · The paper itself

Abstract

backgroundPrevious studies have reported that Black children with food allergy (FA) have higher risk of atopic comorbidities than White children.

objectiveOur study sought to understand if disparities in the prevalence of atopic comorbidities among children with FA are driven by individual and community-level socioeconomic status (SES).

methodsWe analyzed data from a prospective, multicenter cohort investigating the natural history of pediatric atopy: the Food Allergy Outcomes Related to White and African American Racial Differences (FORWARD) study. A validated, multicomponent area deprivation index (ADI) percentile score was tabulated by the census block group for each subject's home address. The association of ADI with atopic comorbidities in FA was assessed via multivariable regression analysis.

resultsOf the 700 children in this study, the mean ADI was 37.7 (95% confidence interval: 35.6-39.7). The mean ADI was higher in children with asthma (43.3) compared with those without asthma (31.8), which remained significant after adjusting for race (P < .0001). Children with allergic rhinitis (AR) had a higher mean ADI (39.1) compared with those without (33.4) (P = .008). ADI was associated with secondhand smoking, parents' education, and household income. Black children had a higher risk for asthma after adjusting for ADI and SES-related factors.

conclusionThe independent association of ADI with asthma and AR, regardless of race, suggests a role of neighborhood-level socioeconomic deprivation in the development of these conditions among children with FA. Black children with FA remained at higher risk for asthma after adjusting for SES-related variables, which can indicate an independent risk for asthma in these children.

Indexed as

AsthmaFood HypersensitivityHypersensitivity, ImmediateRhinitis, AllergicAllergensChildHumansPrevalenceProspective StudiesAllergensAllergic rhinitisAsthmaDisparitiesEczemaFood allergyFORWARDRaceSocioeconomic

Identifiers

PMID36720389
PMCPMC10085831
OpenAlexW4318323664

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.