Evidence map›Paper›PMID 36724227›Full record

ArticleScience advances2023

Big data mining, rational modification, and ancestral sequence reconstruction inferred multiple xylose isomerases for biorefinery.

Sitong Chen, Zhaoxian Xu, Boning Ding, Yuwei Zhang, Shuangmei Liu, Chenggu Cai, Muzi Li, Bruce E Dale, Mingjie Jin

Abstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. A frameshift mutation drives divergent biosynthesis of metallophores inbioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Article
  4. Challenging Pretreatment Technologies of Lignocellulosic Biomass.Advances in biochemical engineering/biotechnology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sitong ChenSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.ORCID 0000-0003-4326-7197
Zhaoxian XuSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.ORCID 0000-0002-0094-3178
Boning DingSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Yuwei ZhangSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Shuangmei LiuSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Chenggu CaiSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.ORCID 0000-0002-4979-0838
Muzi LiSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Bruce E DaleBiomass Conversion Research Laboratory, Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-6120-7406
Mingjie JinSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.ORCID 0000-0002-9493-305X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The isomerization of xylose to xylulose is considered the most promising approach to initiate xylose bioconversion. Here, phylogeny-guided big data mining, rational modification, and ancestral sequence reconstruction strategies were implemented to explore new active xylose isomerases (XIs) for

Indexed as

Saccharomyces cerevisiaeXyloseData MiningFermentationXylose

Identifiers

PMID36724227
PMCPMC9891696

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.