Evidence map›Paper›PMID 36726689›Full record

ArticleFrontiers in immunology2023

Chronic exposure to low-level lipopolysaccharide dampens influenza-mediated inflammatory response

Yinuo Gu, Alan Chen-Yu Hsu, Xu Zuo, Xiaoping Guo, Zhengjie Zhou, Shengyu Jiang, Zhuoer Ouyang, Fang Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Yinuo GuDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Alan Chen-Yu HsuSignature Research Program in Emerging Infectious Diseases, Duke - National University of Singapore (NUS) Graduate Medical School, Singapore, Singapore.
Xu ZuoDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Xiaoping GuoDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Zhengjie ZhouDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Shengyu JiangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Zhuoer OuyangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Fang WangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun, China.
Jilin University · CNUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A virus (IAV) infection leads to severe inflammation, and while epithelial-driven inflammatory responses occur

Indexed as

Influenza, HumanNF-kappa BHumansInflammationLipopolysaccharidesPeroxisome Proliferator-Activated ReceptorsTumor Necrosis Factor alpha-Induced Protein 3LipopolysaccharidesNF-kappa BPeroxisome Proliferator-Activated ReceptorsTumor Necrosis Factor alpha-Induced Protein 3A20 (TNFAIP3)IAVNF-κBNLRP3 inflammasomePPAR

Identifiers

PMID36726689
PMCPMC9886269
OpenAlexW4316363553

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.