Evidence map›Paper›PMID 36726986›Full record

ArticleFrontiers in immunology2022

Adenosine receptors differentially mediate enteric glial cell death induced by

Deiziane V S Costa, Jae H Shin, Sophia M Goldbeck, David T Bolick, Flavio S Mesquita, Andrea V Loureiro, Mônica J Rodrigues-Jesus, Gerly A C Brito, Cirle A Warren

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

  1. CSPG4 Mediates Inflammatory, Cell Death, and Senescence Responses in Enteric Glia Exposed to Clostridioides difficile Toxins.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. The Physiology of Enteric Glia.Annual review of physiology · 2025
    Review
  9. Article
  10. Mechanisms ofFrontiers in cellular and infection microbiology · 2025
    Review
  11. Clinical microbiology reviews · 2024
    Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Deiziane V S CostaDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
Jae H ShinDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
Sophia M GoldbeckDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
David T BolickDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
Flavio S MesquitaDepartment of Microbiology, University of Sao Paulo, Sao Paulo, Brazil.
Andrea V LoureiroDepartment of Morphology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Mônica J Rodrigues-JesusDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
Gerly A C BritoDepartment of Morphology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Cirle A WarrenDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
University of Virginia · USUniversidade Federal do Ceará · BRUniversidade de São Paulo · BR

Funding

Adenosine receptor-mediated effects of Clostridium difficile toxins in humansR21AI119418 · NIAID · UNIVERSITY OF VIRGINIA · PI WARREN, CIRLE ALCANTARA · 2016 to 2017
$435k
NIAID NIH HHS R21 AI119418
6 · The paper itself

Abstract

Increased risk of intestinal dysfunction has been reported in patients after

Indexed as

Bacterial ToxinsClostridioides difficileClostridium InfectionsAnimalsApoptosisBacterial ProteinsBoron CompoundsMiceNeurogliaRatsReceptors, Purinergic P1Bacterial ProteinsBacterial ToxinsBoron CompoundsReceptors, Purinergic P1trimethylaminocarboxyldihydroboranadenosine receptorscell deathClostridioides difficileClostridioides difficile infectionenteric glia

Identifiers

PMID36726986
PMCPMC9885079
OpenAlexW4316363560

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.