ArticleSleep2023
The role of sleep and heart rate variability in metabolic syndrome: evidence from the Midlife in the United States study.
Article in Sleep, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Dynamic Sleep-Derived Heart Rate and Heart Rate Variability Features Associated with Glucose Metabolism Status: An Exploratory Feature-Selection Study Using Consumer Wearables.Sensors (Basel, Switzerland) · 2026Article
- The interaction between exercise and sleep with heart rate variability: cross-sectional study.European journal of applied physiology · 2026Article
- Review
- Machine learning-based early screening of mild cognitive impairment using nutrition-related biomarkers and functional indicators.Frontiers in aging neuroscience · 2025Article
- Deriving Accurate Nocturnal Heart Rate, rMSSD and Frequency HRV from the Oura Ring.Sensors (Basel, Switzerland) · 2024Article
- Re-Evaluating Recommended Optimal Sleep Duration: A Perspective on Sleep Literacy.Children (Basel, Switzerland) · 2024Review
- Pulse Proteins and Their Hydrolysates: A Comprehensive Review of Their Beneficial Effects on Metabolic Syndrome and the Gut Microbiome.Nutrients · 2024Review
- Heart Rate Variability and Cognition: A Narrative Systematic Review of Longitudinal Studies.Journal of clinical medicine · 2024Review
- Sleep disorders and cancer incidence: examining duration and severity of diagnosis among veterans.Frontiers in oncology · 2024Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
STUDY
objectivesPoor sleep and autonomic dysregulation can both disrupt metabolic processes. This study examined the individual and combined effects of poor sleep and reduced heart rate variability (HRV) on metabolic syndrome among 966 participants in the Midlife in the United States II (MIDUS II) study.
methodsSelf-reported sleep was assessed using the Pittsburgh Sleep Quality Index (PSQI). HRV was acquired from 11-minute resting heart rate recordings. Spearman correlations, general linear regression, and logistic regression models were used to examine the study hypotheses.
resultsPoor sleep quality was associated with metabolic syndrome when global PSQI scores were evaluated as a continuous (odds ratio [OR]: 1.07, 95% confidence interval [CI]: 1.03 to 1.11) or categorical measure (cutoff > 5, OR: 1.58, 95% CI: 1.19 to 2.10), after adjustment for confounding. There also was an association between reduced HRV and metabolic syndrome (ln [HF-HRV] OR: 0.89, 95% CI: 0.80 to 0.99; ln [LF-HRV] OR: 0.82, 95% CI: 0.72 to 0.92; ln [SDRR] OR: 0.59, 95% CI: 0.43 to 0.79; ln [RMSSD] OR: 0.75, 95% CI: 0.60 to 0.94). When the combined effects of poor sleep and low HRV were examined, the association with metabolic syndrome was further strengthened relative to those with normal sleep and HRV.
conclusionsTo the best of the author's knowledge, this is the first study to suggest a combined effect of poor sleep and low HRV on the odds of metabolic syndrome.
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