ArticleNature immunology2023
Phosphoinositide acyl chain saturation drives CD8
Abstract read
In one paragraph
Article in Nature immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Body mass index and dyslipidemia influence responses to anti-PD-1 immunotherapy in colorectal cancer.Annals of medicine · 2026Article
- A catalytically competent sperm PLCzeta variant causes fertilization failure through protein insufficiency.Journal of assisted reproduction and genetics · 2026Article
- PIP4K2A: A Novel CD8+ T Cell-Related Biomarker Associated with Lung Function Decline in COPD.Biochemical genetics · 2026Article
- The interplay between lipid metabolism, cancer progression and anti-cancer immunity.Experimental & molecular medicine · 2026Review
- Decoding protein-phospholipid interaction networks in cancer: the role of acyl-chain remodeling.RSC chemical biology · 2026Review
- A Multimodal Imaging Pipeline for the Discovery of Molecular Markers of Cellular Neighborhoods.bioRxiv : the preprint server for biology · 2026Article
- Thy1 retroviral reporters: a versatile platform for congenic background-independent adoptive transfer and CD8Frontiers in immunology · 2026Article
- TGF-βRII/IL-15 immunotherapeutic complex targets exhausted CD8Journal for immunotherapy of cancer · 2025Article
- Identifying Biomedical Entities for Datasets in Scientific Articles: 4-Step Cache-Augmented Generation Approach Using GPT-4o and PubTator 3.0.JMIR formative research · 2025Article
- Pantothenate kinase 4 controls lipid synthesis for T-cell proliferation by modulating coenzyme A and glutaminolysis.Signal transduction and targeted therapy · 2025Article
- Glucose-dependent glycosphingolipid biosynthesis fuels CD8Cell metabolism · 2025Article
- The influence of metabolic disorders on adaptive immunity.Cellular & molecular immunology · 2024Review
- The ATP-exporting channel Pannexin 1 promotes CD8iScience · 2024Article
- GLUT1 overexpression enhances CAR T cell metabolic fitness and anti-tumor efficacy.Molecular therapy : the journal of the American Society of Gene Therapy · 2024Article
- Immunometabolism of CD8Trends in cancer · 2024Review
- Recombinant biosensors for multiplex and super-resolution imaging of phosphoinositides.The Journal of cell biology · 2024Article
- The ATP-exporting channel Pannexin-1 promotes CD8bioRxiv : the preprint server for biology · 2024Article
- Nutrients: Signal 4 in T cell immunity.The Journal of experimental medicine · 2024Article
- Metabolic waypoints during T cell differentiation.Nature immunology · 2024Review
- Nutrient inputs and social metabolic control of T cell fate.Cell metabolism · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
36 authors.
Joy Edwards-Hicks *Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Petya Apostolova *Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0002-3856-5109
Joerg M BuescherMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0002-6547-0076
Hannes MaibDivision of Cell & Developmental Biology, School of Life Sciences, University of Dundee, Dundee, UK.
Michal A StanczakMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Mauro CorradoMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0002-0617-3274
Ramon I Klein GeltinkMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0003-4610-3059
Maria Elena MaccariCenter for Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Matteo VillaMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0003-2684-0596
Gustavo E CarrizoMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
David E SaninMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0003-0188-7267
Francesc BaixauliMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Beth KellyMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Jonathan D CurtisMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Fabian HaesslerMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0002-0038-9429
Annette PattersonMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Cameron S FieldMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
George CaputaMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Ryan L KyleMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0002-8146-7504
Melanie SoballaMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Minsun ChaBloomberg-Kimmel Institute for Cancer Immunotherapy and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Harry PaulBloomberg-Kimmel Institute for Cancer Immunotherapy and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-8799-4954
Jacob MartinBloomberg-Kimmel Institute for Cancer Immunotherapy and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-2193-0453
Katarzyna M GrzesMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Lea FlachsmannMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Michael MittererMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Liang ZhaoBloomberg-Kimmel Institute for Cancer Immunotherapy and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-2126-6778
Frances WinklerClinic for Internal Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
David Ali Rafei-ShamsabadiDepartment of Dermatology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Frank MeissDepartment of Dermatology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Bertram BengschClinic for Internal Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-2552-740X
Robert ZeiserSignaling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-6565-3393
Daniel J PulestonMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0002-8437-0732
David O'SullivanMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0001-5151-8924
Edward J PearceMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Erika L PearceMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany. epearce6@jhmi.edu.ORCID http://orcid.org/0000-0001-5592-5439
Funding
Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4MPhosphorylation of TSC2 (S1365) as a novel Regulator of mTORC1 Signaling in T CellsR01AI156274 · NIAID · JOHNS HOPKINS UNIVERSITY · PI PEARCE, ERIKA L · 2021 to 2025
$2.6MNIAID NIH HHS R01 AI156274NIGMS NIH HHS T32 GM136577Wellcome Trust
Abstract
How lipidome changes support CD8
Indexed as
Phosphatidylinositol PhosphatesPhosphatidylinositolsCD8-Positive T-LymphocytesSignal TransductionType C PhospholipasesPhosphatidylinositol PhosphatesPhosphatidylinositolsType C Phospholipases
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.