Evidence map›Paper›PMID 36733248›Full record

ReviewCurrent cardiology reviews2023

Role of Gut Microbiome in Atherosclerosis: Molecular and Therapeutic Aspects.

Juan Salazar, Valery Morillo, María K Suárez, Ana Castro, Paola Ramírez, Milagros Rojas, Roberto Añez, Luis D'Marco, Maricarmen Chacín-González, Valmore Bermúdez

Open access · greenAbstract readReview
In one paragraph

Review in Current cardiology reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The Role of the Gut Microbiota in Vascular Physiology and Health.International journal of molecular sciences · 2025
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Juan SalazarEndocrine and Metabolic Disease Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Valery MorilloEndocrine and Metabolic Disease Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
María K SuárezEndocrine and Metabolic Disease Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Ana CastroEndocrine and Metabolic Disease Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Paola RamírezEndocrine and Metabolic Disease Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Milagros RojasEndocrine and Metabolic Disease Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.
Roberto AñezDepartamento de Endocrinología y Nutrición. Hospital General Universitario Gregorio Marañón, Madrid, España.
Luis D'MarcoUniversidad Cardenal Herrera-CEU, CEU Universities, Valencia, 46115, Spain.
Maricarmen Chacín-GonzálezUniversidad Simón Bolívar, Facultad de Ciencias de la Salud, Barranquilla, Colombia.
Valmore BermúdezUniversidad Simón Bolívar, Facultad de Ciencias de la Salud, Barranquilla, Colombia.
University of Zulia · VEUniversidad Simón Bolívar · COHospital General Universitario Gregorio Marañón · ESUniversidad Cardenal Herrera CEU · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is one of the most relevant and prevalent cardiovascular diseases of our time. It is one of the pathological entities that increases the morbidity and mortality index in the adult population. Pathophysiological connections have been observed between atherosclerosis and the gut microbiome (GM), represented by a group of microorganisms that are present in the gut. These microorganisms are vital for metabolic homeostasis in humans. Recently, direct and indirect mechanisms through which GM can affect the development of atherosclerosis have been studied. This has led to research into the possible modulation of GM and metabolites as a new target in the prevention and treatment of atherosclerosis. The goal of this review is to analyze the physiopathological mechanisms linking GM and atherosclerosis that have been described so far. We also aim to summarize the recent studies that propose GM as a potential target in atherosclerosis management.

Indexed as

AtherosclerosisCardiovascular DiseasesGastrointestinal MicrobiomeHumansAtherosclerosisdysbiosisgutinflammationmicrobiometreatment

Identifiers

PMID36733248
PMCPMC10494273
OpenAlexW4319061392

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.