Evidence map›Paper›PMID 36733805›Full record

ReviewFrontiers in endocrinology2022

Endocrine disorders and fertility and pregnancy: An update.

Anna Bendarska-Czerwińska, Nikola Zmarzły, Emilia Morawiec, Agata Panfil, Kamil Bryś, Justyna Czarniecka, Aleksander Ostenda, Konrad Dziobek, Dorota Sagan, Dariusz Boroń and 3 more

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Molecular mechanisms of ovarian fibrosis.Molecular human reproduction · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anna Bendarska-CzerwińskaDepartment of Molecular, Biology Gyncentrum Fertility Clinic, Katowice, Poland.
Nikola ZmarzłyDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, Poland.
Emilia MorawiecDepartment of Molecular, Biology Gyncentrum Fertility Clinic, Katowice, Poland.
Agata PanfilDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, Poland.
Kamil BryśDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, Poland.
Justyna CzarnieckaDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, Poland.
Aleksander OstendaFaculty of Medicine, Academy of Silesia, Zabrze, Poland.
Konrad DziobekFaculty of Medicine, Academy of Silesia, Zabrze, Poland.
Dorota SaganMedical Center Dormed Medical SPA, Busko-Zdroj, Poland.
Dariusz BorońDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology, Academy of Silesia in Katowice, Zabrze, Poland.
Piotr MichalskiFaculty of Medicine, Academy of Silesia, Zabrze, Poland.
Veronica Pallazo-MichalskaFaculty of Medicine, Academy of Silesia, Zabrze, Poland.
Beniamin Oskar GrabarekDepartment of Molecular, Biology Gyncentrum Fertility Clinic, Katowice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is estimated that more and more couples suffer from fertility and pregnancy maintenance disorders. It is associated with impaired androgen secretion, which is influenced by many factors, ranging from genetic to environmental. It is also important to remember that fertility disorders can also result from abnormal anatomy of the reproductive male and female organ (congenital uterine anomalies - septate, unicornuate, bicornuate uterus; acquired defects of the uterus structure - fibroids, polyps, hypertrophy), disturbed hormonal cycle and obstruction of the fallopian tubes resulting from the presence of adhesions due to inflammation, endometriosis, and surgery, abnormal rhythm of menstrual bleeding, the abnormal concentration of hormones. There are many relationships between the endocrine organs, leading to a chain reaction when one of them fails to function properly. Conditions in which the immune system is involved, including infections and autoimmune diseases, also affect fertility. The form of treatment depends on infertility duration and the patient's age. It includes ovulation stimulation with clomiphene citrate or gonadotropins, metformin use, and weight loss interventions. Since so many different factors affect fertility, it is important to correctly diagnose what is causing the problem and to modify the treatment regimen if necessary. This review describes disturbances in the hormone secretion of individual endocrine organs in the context of fertility and the maintenance of pregnancy.

Indexed as

Endocrine System DiseasesInfertilityLeiomyomaClomipheneFemaleFertilityHumansMalePregnancyReproductionUterusClomipheneendocrine disordersfertilityhormonesinfertilitypregnancyreproductive health

Identifiers

PMID36733805
PMCPMC9887196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.