Evidence map›Paper›PMID 36735291›Full record

ArticleeLife2023

Peroxiredoxin 5 regulates osteogenic differentiation through interaction with hnRNPK during bone regeneration.

Eunjin Cho, Xiangguo Che, Mary Jasmin Ang, Seongmin Cheon, Jinkyung Lee, Kwang Soo Kim, Chang Hoon Lee, Sang-Yeop Lee, Hee-Young Yang, Changjong Moon and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Hnrnpk protects against osteoarthritis through targeting WWC1 mRNA and inhibiting Hippo signaling pathway.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Eunjin Cho *Department of Oral Biochemistry, Korea Mouse Phenotype Center (KMPC), Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.ORCID 0000-0003-0276-4728
Xiangguo Che *Department of Biochemistry and Cell Biology, BK21 Plus KNU Biomedical Convergence Program, Skeletal Diseases Analysis Center, Korea Mouse Phenotyping Center (KMPC), School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Mary Jasmin AngDepartment of Basic Veterinary Sciences, College of Veterinary Medicine, University of the Philippines Los Baños, Los Baños, Philippines.
Seongmin CheonSchool of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea.
Jinkyung LeeDepartment of Oral Biochemistry, Korea Mouse Phenotype Center (KMPC), Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.
Kwang Soo KimDepartment of Microbiology, Department of Molecular Medicine (BK21plus), Chonnam National University Medical School, Gwangju, Republic of Korea.
Chang Hoon LeeTherapeutic & Biotechnology Division, Drug Discovery Platform Research Center, Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea.ORCID 0000-0001-8953-9069
Sang-Yeop LeeResearch Center for Bioconvergence Analysis, Korea Basic Science Institute, Ochang, Republic of Korea.
Hee-Young YangPreclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.
Changjong MoonDepartment of Veterinary Anatomy and Animal Behavior, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju, Republic of Korea.ORCID 0000-0003-2451-0374
Chungoo ParkSchool of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea.
Je-Yong ChoiDepartment of Biochemistry and Cell Biology, BK21 Plus KNU Biomedical Convergence Program, Skeletal Diseases Analysis Center, Korea Mouse Phenotyping Center (KMPC), School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Tae-Hoon LeeDepartment of Oral Biochemistry, Korea Mouse Phenotype Center (KMPC), Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.ORCID 0000-0003-0105-1750
Chonnam National University · KRKyungpook National University · KRDaegu-Gyeongbuk Medical Innovation Foundation · KRInstitute of Chemical Technology · INKorea Basic Science Institute · KRUniversity of the Philippines Los Baños · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroxiredoxin 5 (Prdx5) is involved in pathophysiological regulation via the stress-induced cellular response. However, its function in the bone remains largely unknown. Here, we show that Prdx5 is involved in osteoclast and osteoblast differentiation, resulting in osteoporotic phenotypes in

Indexed as

Heterogeneous-Nuclear Ribonucleoprotein KOsteogenesisAnimalsBone RegenerationCell DifferentiationChromatography, LiquidMaleMiceOsteoblastsOsteoclastsPeroxiredoxinsTandem Mass SpectrometryHeterogeneous-Nuclear Ribonucleoprotein KPeroxiredoxinsPrdx5 protein, mousebone regenerationcell biologydevelopmental biologymouseosteoblastosteoclastosteoporosisperoxiredoxin

Identifiers

PMID36735291
PMCPMC9897727
OpenAlexW4318825827

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.