Evidence map›Paper›PMID 36740354›Full record

ReviewThe Psychiatric clinics of North America2023

Genomics of Obsessive-Compulsive Disorder and Related Disorders: What the Clinician Needs to Know.

James J Crowley

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Psychiatric clinics of North America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

James J CrowleyDepartment of Genetics, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Chapel Hill, NC 27599, USA; Department of Psychiatry, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Chapel Hill, NC 27599, USA. Electronic address: crowley@unc.edu.

Funding

Latino Ancestry Genomic Psychiatry CohortR01MH123451 · NIMH · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2023 to 2025
$2.8M
2/2 Rare Genetic Variation and Risk for Obsessive Compulsive DisorderR01MH124675 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · 2022 to 2025
$665k
1/2 Trans-ancestry genomic analysis of obsessive-compulsive disorderU01MH125050 · UNIV OF NORTH CAROLINA CHAPEL HILL · 2025 to 2025
$386k
NIMH NIH HHS R01 MH110427NIMH NIH HHS R01 MH123451NIMH NIH HHS R01 MH124675NIMH NIH HHS U01 MH125050
6 · The paper itself

Abstract

A wealth of evidence has shown that genetics plays a major role in susceptibility to obsessive-compulsive disorder (OCD) and all of its related disorders. Several large-scale, collaborative efforts using modern genomic methods are beginning to reveal the genetic architecture of these traits and identify long-sought risk genes. In this article, we summarize current OCD and related disorder genomic knowledge and explain how to communicate this information to patients and their families. The article concludes with a discussion of how genomic discovery in OCD and related disorders can inform our understanding of disease etiology and provide novel targets for therapeutic development.

Indexed as

Body Dysmorphic DisordersObsessive-Compulsive DisorderTrichotillomaniaGenomicsHumansBody dysmorphic disorderExcoriation disorderGeneticGenomicHoarding disorderObsessive-compulsive disorderTrichotillomaniaTwin

Identifiers

PMID36740354
PMCPMC10191614

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.