Evidence map›Paper›PMID 36741065›Full record

Trial reportWorld journal of gastrointestinal surgery2023

Short-term efficacy assessment of transarterial chemoembolization combined with radioactive iodine therapy in primary hepatocellular carcinoma.

Lei Wang, Kun Huang, Yu Zhang, Yi-Fan Wu, Zhen-Dong Yue, Zhen-Hua Fan, Fu-Quan Liu, Yong-Wu Li, Jian Dong

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of gastrointestinal surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lei WangDepartment of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Kun HuangDepartment of Radiology, Chinese Medical University Affiliated First Hospital, Shenyang 110001, Liaoning Province, China.
Yu ZhangDepartment of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Yi-Fan WuDepartment of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Zhen-Dong YueDepartment of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Zhen-Hua FanDepartment of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Fu-Quan LiuDepartment of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Yong-Wu LiDepartment of Nuclear Medicine, The Fifth Center of People's Liberation Army General Hospital, Beijing 100071, China.
Jian DongDepartment of Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China. dongjianradiology@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransarterial chemoembolization (TACE) is an effective treatment for primary hepatocellular carcinoma (PHC). Radioactive iodine therapy has been used in the treatment of advanced PHC, especially in patients with portal vein tumor thrombosis. However, data on the therapeutic effect of TACE combined with radioactive iodine therapy in PHC are scarce.

aimTo investigate the clinical efficacy of TACE combined with radioactive iodine implantation therapy in advanced PHC

methodsFor this study, 98 advanced PHC patients were recruited and divided randomly into the study and control groups. Patients in the study group were treated with TACE combined radioactive iodine implantation therapy. Patients in the control group were treated with only TACE. The tumor lesion length, clinical effect, serum alpha-fetoprotein (AFP) and CT perfusion parameters were compared before and after therapy, and statistical analysis was performed.

resultsThere was no significant difference in tumor length and serum AFP between the study and control groups (

conclusionTACE combined with radioactive iodine implantation in the treatment of advanced PHC can inhibit the formation of blood vessels in tumor tissue and reduce the perfusion level of tumor lesions, thereby improving the clinical efficacy and prolonging the survival time of patients.

Indexed as

Computed tomographyPerfusionPrimary hepatocellular carcinomaRadioactive iodineTransarterial chemoembolization

Identifiers

PMID36741065
PMCPMC9896495

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.