Evidence map›Paper›PMID 36741147›Full record

ArticleRSC advances2023

A novel and sensitive ratiometric fluorescent quantum dot-based biosensor for alkaline phosphatase detection in biological samples

Penghui Hu, Ruiyan Huang, Ye Xu, Tengfei Li, Jun Yin, Yu Yang, Yuan Liang, Xiaohan Mao, Li Ding, Chang Shu

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. A turn-on chemiluminescent assay for alkaline phosphatase using two-dimensional Fe-centered metal-organic frameworks as the signaling probe.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Penghui HuKey Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education Nanjing 210009 China shuchang@cpu.edu.cn.
Ruiyan HuangKey Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education Nanjing 210009 China shuchang@cpu.edu.cn.
Ye XuKey Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education Nanjing 210009 China shuchang@cpu.edu.cn.
Tengfei LiDepartment of Clinical Pharmacology, School of Pharmacy, Sir Run Run Hospital, Nanjing Medical University Nanjing 211166 China.
Jun YinKey Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education Nanjing 210009 China shuchang@cpu.edu.cn.
Yu YangKey Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education Nanjing 210009 China shuchang@cpu.edu.cn.
Yuan LiangKey Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education Nanjing 210009 China shuchang@cpu.edu.cn.
Xiaohan MaoDepartment of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University Nanjing 211198 China.
Li DingKey Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education Nanjing 210009 China shuchang@cpu.edu.cn.ORCID https://orcid.org/0000-0003-2813-0985
Chang ShuKey Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education Nanjing 210009 China shuchang@cpu.edu.cn.ORCID https://orcid.org/0000-0001-5691-6673
China Pharmaceutical University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alkaline phosphatase (ALP) is an important biomarker whose abnormal level in activity is associated with hepatobiliary, skeletal, and renal diseases as well as cancer. Herein, we synthesized ZnSe@ZnS quantum dots (ZnSe@ZnS QDs) and Mn-doped ZnS quantum dots (Mn:ZnS QDs) as fluorophores to establish the ratiometric fluorescent assay for ALP activity detection in biological samples.

Identifiers

PMID36741147
PMCPMC9841509
OpenAlexW4316466942

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.