Evidence map›Paper›PMID 36744101›Full record

ReviewFrontiers in behavioral neuroscience2022

Evaluating depression- and anxiety-like behaviors in non-human primates.

Karla K Ausderau, Ricki J Colman, Sabrina Kabakov, Nancy Schultz-Darken, Marina E Emborg

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Karla K AusderauWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Ricki J ColmanWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Sabrina KabakovDepartment of Kinesiology, University of Wisconsin-Madison, Madison, WI, United States.
Nancy Schultz-DarkenWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Marina E EmborgWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
University of Wisconsin–Madison · US

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Modeling Frontotemporal Dementia in Rhesus MacaquesR33NS115102 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI CHEN, RUI, EMBORG, MARINA · 2022 to 2024
$1.8M
NIH HHS P51 OD011106NINDS NIH HHS R33 NS115102
6 · The paper itself

Abstract

Depression and anxiety are some of the most prevalent and debilitating mental health conditions in humans. They can present on their own or as co-morbidities with other disorders. Like humans, non-human primates (NHPs) can develop depression- and anxiety-like signs. Here, we first define human depression and anxiety, examine equivalent species-specific behaviors in NHPs, and consider models and current methods to identify and evaluate these behaviors. We also discuss knowledge gaps, as well as the importance of evaluating the co-occurrence of depression- and anxiety-like behaviors in animal models of human disease. Lastly, we consider ethical challenges in depression and anxiety research on NHPs in order to ultimately advance the understanding and the personalized treatment of these disorders.

Indexed as

anxietydepressionmacaquemarmosetnon-human primates

Identifiers

PMID36744101
PMCPMC9892652
OpenAlexW4317387819

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.