Evidence map›Paper›PMID 36746250›Full record

ArticleChemosphere2023

Metabolomic changes associated with chronic arsenic exposure in a Bangladeshi population.

Haotian Wu, Vrinda Kalia, Megan M Niedzwiecki, Marianthi-Anna Kioumourtzoglou, Brandon Pierce, Vesna Ilievski, Jeff Goldsmith, Dean P Jones, Ana Navas-Acien, Douglas I Walker and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemosphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Arsenome, Arsenobolome, and Arsenobiolome.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Haotian WuDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Vrinda KaliaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Megan M NiedzwieckiDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Marianthi-Anna KioumourtzoglouDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Brandon PierceDepartment of Public Health Sciences, University of Chicago, Chicago, IL, USA; Department of Human Genetics, University of Chicago, Chicago, IL, USA; Comprehensive Cancer Center, University of Chicago, Chicago, IL, USA.
Vesna IlievskiDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Jeff GoldsmithDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.
Dean P JonesDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, USA; Department of Biochemistry, Emory University School of Medicine, Atlanta, USA.
Ana Navas-AcienDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Douglas I WalkerGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA. Electronic address: douglas.walker@emory.edu.
Mary V GambleDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA. Electronic address: mvg7@cumc.columbia.edu.
Columbia University · USEmory University · USChicago Department of Public Health · USColumbia University Irving Medical Center · USIcahn School of Medicine at Mount Sinai · US

Funding

Training CoreP42ES010349 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NAVAS-ACIEN, ANA · 2000 to 2020
$53.6M
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Steven N. Chillrud · 1998 to 2026
$44.7M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
Research Experience and Training Coordination CoreP42ES033719 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Ana Navas-Acien · 2022 to 2026
$11.9M
Metabolomic and nutrigenetic effects of folic acid supplementation and unmetabolized folic acidR01DK123285 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAMBLE, MARY · 2020 to 2023
$2.6M
Mapping the blood cancer exposome for environmental risk profiles of mature B-cell neoplasmsR01ES032831 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Douglas Ian Walker · 2022 to 2026
$2.3M
Folic Acid and Creatine as Therapeutic Approaches for Lowering Blood ArenicR01CA133595 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAMBLE, MARY · 2009 to 2013
$2.3M
Principal Component Pursuit to Assess Exposure to Environmental Mixtures in Epidemiologic StudiesR01ES028805 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KIOUMOURTZOGLOU, MARIANTHI-ANNA · 2018 to 2021
$2.2M
Interdisciplinary approaches for understanding the metabolic effects of arsenic and manganeseR01ES030945 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAMBLE, MARY · 2020 to 2022
$1.9M
NCI NIH HHS R01 CA133595NIDDK NIH HHS R01 DK123285NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P30 ES019776NIEHS NIH HHS P30 ES027792NIEHS NIH HHS P42 ES010349NIEHS NIH HHS P42 ES033719NIEHS NIH HHS R01 ES028805NIEHS NIH HHS R01 ES030945NIEHS NIH HHS R01 ES032831
6 · The paper itself

Abstract

Chronic exposure to arsenic (As) remains a global public health concern and our understanding of the biological mechanisms underlying the adverse effects of As exposure remains incomplete. Here, we used a high-resolution metabolomics approach to examine how As affects metabolic pathways in humans. We selected 60 non-smoking adults from the Folic Acid and Creatine Trial (FACT). Inorganic (As

Indexed as

ArsenicArsenicalsAdultCacodylic AcidEnvironmental ExposureFolic AcidHumansMetabolomeMetabolomicsArsenicArsenicalsCacodylic Aciddimethylarsinous acidFolic AcidArsenicFolateFolic acidMetabolomicsOne carbon metabolismTCA cycle

Identifiers

PMID36746250
PMCPMC9993428
OpenAlexW4319230193

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.