ArticleBMC geriatrics2023
Triglyceride glucose index predicts all-cause mortality in oldest-old patients with acute coronary syndrome and diabetes mellitus.
Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Does diabetes status modify the association between the triglyceride-glucose index and major adverse cardiovascular events in patients with coronary heart disease? A systematic review and meta-analysis of longitudinal cohort studies.Cardiovascular diabetology · 2025Pooled it
- Does diabetes modify the triglyceride-glucose index associated with cardiovascular events and mortality? A meta-analysis of 50 cohorts involving 7,239,790 participants.Cardiovascular diabetology · 2025Pooled it
- Effects of aerobic exercise on cognitive function in older adults with mild cognitive impairment: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Optimal dose and type of exercise to improve cognitive function in patients with mild cognitive impairment: a systematic review and network meta-analysis of RCTs.Frontiers in psychiatry · 2024Pooled it
- Triglyceride-glucose index and coronary artery disease: a systematic review and meta-analysis of risk, severity, and prognosis.Cardiovascular diabetology · 2023Pooled it
- The Lipid Paradox in Statin-Naïve Patients with a First ST-Segment Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention: A Confounded, Not Protective, Association.Journal of clinical medicine · 2026Article
- The Association Between Triglyceride-Glucose Index and Mortality Risk in Cardiovascular Disease Patients: A Meta-Analysis.Journal of clinical medicine research · 2026Article
- Nonlinear Relationship Between the Triglyceride-Glucose Index and All-Cause and Cardiovascular Mortality in Diabetes Mellitus Patients With Hypertension: A National Cohort Study.International journal of endocrinology · 2026Article
- Triglyceride-glucose index is associated with the severity of coronary artery disease.PloS one · 2026Article
- Observational
- The role of frailty in older adults with Non-ST-elevation acute coronary syndrome: a Chinese population-based cohort study.Aging clinical and experimental research · 2025Article
- The triglyceride glucose-waist circumference index is a predictor of obstructive sleep apnea risk and all-cause and cardiovascular mortality.Scientific reports · 2025Article
- Association of triglyceride-glucose index with all-cause and non-cardiovascular mortality in patients with obstructive sleep apnea: an age-stratified analysis.Diabetology & metabolic syndrome · 2025Article
- Inverse L-shaped association of triglyceride glucose index with all-cause and cerebral cardiovascular-related mortality in osteoarthritis patients: a cohort of 4145 patients.Clinical rheumatology · 2025Article
- Triglyceride glucose index predicts long-term mortality and major adverse cardiovascular events in patients with type 2 diabetes.Cardiovascular diabetology · 2025Article
- Triglyceride-glucose index is associated with microcirculatory resistance in patients with type 2 diabetes and STEMI undergoing primary PCI.Scientific reports · 2025Observational
- Association of the triglyceride glucose index with all cause and CVD mortality in the adults with diabetes aged < 65 years without cardiovascular disease.Scientific reports · 2025Article
- Article
- Association Between the Triglyceride-Glucose Index and All-Cause Mortality Among Patients with Diabetes and Chronic Kidney Disease: A Retrospective Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Association between Triglyceride-Glucose Index and Prognosis in Critically Ill Patients with Acute Coronary Syndrome: Evidence from the MIMIC Database.International journal of medical sciences · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute coronary syndrome (ACS) and diabetes mellitus (DM) are the leading health risks for the elderly. Triglyceride-glucose (TyG) index is a novel and reliable indicator of insulin resistance (IR). This study aims to explore the relationship between the TyG index and all-cause mortality in oldest-old patients with ACS and DM.
methodsSeven hundred twenty hospitalized patients with ACS aged ≥ 80 years were enrolled, and 699 patients signed informed consent for the study. During the follow-up period, 37 were lost to follow-up, and the follow-up rate was 94.7%. 231 ACS patients with DM were selected for the study's analyses. Kaplan-Meier curve, Cox regression model and receiver operating characteristic (ROC) curve were used to analyze the association between the TyG index and all-cause mortality.
resultsThe mean age of participants was 81.58 ± 1.93 years, and 32.47% were women. Compared to TyG tertile 1, the Hazard Ratio (HR) [95% confidence interval (CI)] of all-cause mortality was 2.04 (1.09, 3.81) for TyG tertile 3 in the fully adjusted model. For the TyG index per standard deviation (SD) increment, the HR (95% CI) of all-cause mortality was 1.44 (1.13, 1.83). Further, the association between the TyG index and all-cause mortality was dose-response (P for trend = 0.026). ROC curve analyses indicated that the TyG index outperformed FBG and TG in the prediction of mortality risk and improved the prognostic value of the Gensini score combined with LVEF.
conclusionThe TyG index predicts the risk of all-cause mortality in the oldest-old ACS patients with DM.
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