Evidence mapPaperPMID 36748934Full record

ReviewArchives of endocrinology and metabolism2023

Hypoglycemia post bariatric surgery: drugs with different mechanisms of action to treat a unique disorder.

Giovanna Braganholo Carpentieri, Sandra Elisa Adami Batista Gonçalves, Walid Mohamed Mourad, Lara Guimarães Carelo Pinto, Maria Teresa Zanella

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Archives of endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07440706 (A Prospective Randomized Study Evaluating the Efficacy and Safety of the iCan i3 Continuous Glucose Monitoring System in Post-Bariatric Patients With Late Dumping Syndrome), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07440706 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Prospective Randomized Study Evaluating the Efficacy and Safety of the iCan i3 Continuous Glucose Monitoring System in Post-Bariatric Patients With Late Dumping Syndrome

TypeinterventionalSponsorKaiser Clinic and HospitalRan2025 to 2026Enrolled60ConditionsDumping Syndrome, Post-bariatric HypoglycemiaArmsCan i3 Continuous Glucose Monitoring System
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Giovanna Braganholo CarpentieriDepartamento de Medicina, Divisão de Endocrinologia e Metabolismo, Universidade Federal de São Paulo, São Paulo, SP, Brasil, gicarpenti@hotmail.com.
Sandra Elisa Adami Batista GonçalvesDepartamento de Medicina, Divisão de Endocrinologia e Metabolismo, Universidade Federal de São Paulo, São Paulo, SP, Brasil.
Walid Mohamed MouradUniversidade Santo Amaro, São Paulo, SP, Brasil.
Lara Guimarães Carelo PintoUniversidade Santo Amaro, São Paulo, SP, Brasil.
Maria Teresa ZanellaDepartamento de Medicina, Divisão de Endocrinologia e Metabolismo, Universidade Federal de São Paulo, São Paulo, SP, Brasil.
Medicina · PLUniversidade de Santo Amaro · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postprandial hypoglycemia (PPH) is a complex and multifactorial complication of bariatric surgery (BS). PPH may cause severe symptoms or be asymptomatic. The treatment of this condition requires dietary changes, but severe cases require drug therapy. The number of therapeutic options is limited and are often associated with adverse side effects. Different classes of drugs have been used and tested, but the resolution of PPH remains a challenge for physicians and patients. In this review, we gathered articles on PPH after BS from PubMed searches (2001 to 2022) and focused on the main drugs tested for the treatment of this condition, such as acarbose, somatostatin analogues, type 2 sodium-glucose cotransporter inhibitors, calcium channel blockers, and liraglutide. Avexitide and glucagon pump are two new therapeutic options that have been recently tested. For the search, the terms "postbariatric hypoglycemia," "bariatric surgery," and "late dumping syndrome" were used. PPH after BS is a frequent condition that should always be evaluated after BS. Treatment should be individualized and the available therapeutic options may be useful based on the condition's pathophysiology.

Indexed as

Bariatric SurgeryGastric BypassHypoglycemiaObesity, MorbidAcarboseBlood GlucoseGlucagonHumansAcarboseBlood GlucoseGlucagonbariatric surgerygastric bypassPostprandial hypoglycemia

Identifiers

PMID36748934
PMCPMC10247255
OpenAlexW4319333092

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.