Evidence map›Paper›PMID 36749071›Full record

ArticleJournal of virology2023

Human Papillomavirus Genome Copy Number Is Maintained by S-Phase Amplification, Genome Loss to the Cytosol during Mitosis, and Degradation in G

Malgorzata Bienkowska-Haba, Katarzyna Zwolinska, Timothy Keiffer, Rona S Scott, Martin Sapp

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Malgorzata Bienkowska-Haba *Department of Microbiology and Immunology, Feist Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Katarzyna Zwolinska *Department of Microbiology and Immunology, Feist Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Timothy KeifferDepartment of Microbiology and Immunology, Feist Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Rona S ScottDepartment of Microbiology and Immunology, Feist Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.ORCID 0000-0003-3840-9189
Martin SappDepartment of Microbiology and Immunology, Feist Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.ORCID 0000-0003-3916-8890
Louisiana State University Health Sciences Center Shreveport · US

Funding

Immediate early events of the HPV life cycleR01CA211576 · NCI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Katarzyna Zwolinska · 2017 to 2026
$2.8M
Epigenetic Effects of Epstein-Barr Virus Infection in Oral Squamous Cell CarcinomaR01DE025565 · NIDCR · LOUISIANA STATE UNIV HSC SHREVEPORT · PI SCOTT, RONA S · 2015 to 2019
$1.8M
HHS | NIH | National Cancer Institute (NCI) R01CA211576HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) R01DE025565NCI NIH HHS R01 CA211576NIDCR NIH HHS R01 DE025565
6 · The paper itself

Abstract

The current model of human papillomavirus (HPV) replication is comprised of three modes of replication. Following infectious delivery, the viral genome is amplified during the establishment phase to reach up to some hundred copies per cell. The HPV genome copy number remains constant during the maintenance stage. The differentiation of infected cells induces HPV genome amplification. Using highly sensitive

Indexed as

DNA Copy Number VariationsHuman Papillomavirus VirusesMitosisOncogene Proteins, ViralVirus ReplicationCytosolDNA, ViralGenome, ViralHuman papillomavirus 16HumansKeratinocytesPapillomavirus InfectionsS PhaseDNA, ViralOncogene Proteins, Viralcytoplasmic papillomavirus genomegenome maintenanceHPV16infection modelprimary foreskin keratinocytesviral genome amplificationviral genome amplification and maintenanceviral genome degradation

Identifiers

PMID36749071
PMCPMC9972943
OpenAlexW4319333291

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.