Evidence map›Paper›PMID 36749320›Full record

ArticleeLife2023

Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast.

Rahul Bhattacharjee, Aaron R Hall, MariaSanta C Mangione, Maya G Igarashi, Rachel H Roberts-Galbraith, Jun-Song Chen, Dimitrios Vavylonis, Kathleen L Gould

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Characterization and comparison ofmicroPublication biology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rahul BhattacharjeeDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, United States.ORCID 0000-0001-8607-5756
Aaron R HallDepartment of Physics, Lehigh University, Bethlehem, United States.ORCID 0000-0002-6194-8060
MariaSanta C MangioneDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, United States.
Maya G IgarashiDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, United States.ORCID 0000-0003-3727-5473
Rachel H Roberts-GalbraithDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, United States.ORCID 0000-0002-2682-2366
Jun-Song ChenDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, United States.
Dimitrios VavylonisDepartment of Physics, Lehigh University, Bethlehem, United States.ORCID 0000-0003-1802-3262
Kathleen L GouldDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, United States.ORCID 0000-0002-3810-4070

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Regulation of cytokinesisR35GM131799 · NIGMS · VANDERBILT UNIVERSITY · PI Kathleen L Gould · 2019 to 2026
$6.4M
Modeling mechanisms in cytokinesis, cell polarization and motilityR35GM136372 · NIGMS · LEHIGH UNIVERSITY · PI Dimitrios Vavylonis · 2020 to 2026
$3.2M
Investigating the Regulation and Structural Features of the conserved Membrane-Binding F-BAR Protein Cdc15F31GM119252 · NIGMS · VANDERBILT UNIVERSITY · PI MANGIONE, MARIASANTA · 2016 to 2017
$57k
NIGMS NIH HHS F31 GM119252NIGMS NIH HHS R35 GM131799NIGMS NIH HHS R35 GM136372NIGMS NIH HHS T32 GM007347
6 · The paper itself

Abstract

The F-BAR protein Cdc15 is essential for cytokinesis in

Indexed as

Cell Cycle ProteinsCytokinesisSchizosaccharomycesSchizosaccharomyces pombe ProteinsCytoskeletal ProteinsGTP-Binding Proteinsp21-Activated KinasesPhosphorylationProtein KinasesProtein Serine-Threonine KinasesCDC15 proteinCell Cycle ProteinsCytoskeletal ProteinsGTP-Binding Proteinskin1 protein, S pombep21-Activated KinasesPom1 protein, S pombeProtein KinasesProtein Serine-Threonine KinasesSchizosaccharomyces pombe Proteinsshk1 protein, S pombecell biologycytokinesisF-BAR proteinfission yeastintrinsically disordered regionphase separationS. pombe

Identifiers

PMID36749320
PMCPMC9904764

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.