Evidence map›Paper›PMID 36753355›Full record

ReviewACS applied bio materials2023

Potential and Progress of 2D Materials in Photomedicine for Cancer Treatment.

Himanshu N Bhatt, Jaqueline Pena-Zacarias, Elfa Beaven, Md Ikhtiar Zahid, Sheikh Shafin Ahmad, Rimpy Diwan, Md Nurunnabi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ACS applied bio materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Himanshu N BhattDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Texas El Paso, El Paso, Texas 79902, United States.
Jaqueline Pena-ZacariasDepartment of Biological Sciences, The University of Texas El Paso, El Paso, Texas 79968, United States.
Elfa BeavenDepartment of Biomedical Engineering, The University of Texas El Paso, El Paso, Texas 79968, United States.
Md Ikhtiar ZahidDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Texas El Paso, El Paso, Texas 79902, United States.
Sheikh Shafin AhmadDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Texas El Paso, El Paso, Texas 79902, United States.
Rimpy DiwanDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Texas El Paso, El Paso, Texas 79902, United States.
Md NurunnabiDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Texas El Paso, El Paso, Texas 79902, United States.ORCID 0000-0003-4457-3401

Funding

Using Common Fund datasets for xenobiotic localizationR03OD032624 · OD · UNIVERSITY OF TEXAS EL PASO · PI NURUNNABI, MD · 2021 to 2021
$304k
NIH HHS R03 OD032624
6 · The paper itself

Abstract

Over the last decades, photomedicine has made a significant impact and progress in treating superficial cancer. With tremendous efforts many of the technologies have entered clinical trials. Photothermal agents (PTAs) have been considered as emerging candidates for accelerating the outcome from photomedicine based cancer treatment. Besides various inorganic and organic candidates, 2D materials such as graphene, boron nitride, and molybdenum disulfide have shown significant potential for photothermal therapy (PTT). The properties such as high surface area to volume, biocompatibility, stability in physiological media, ease of synthesis and functionalization, and high photothermal conversion efficiency have made 2D nanomaterials wonderful candidates for PTT to treat cancer. The targeting or localized activation could be achieved when PTT is combined with chemotherapies, immunotherapies, or photodynamic therapy (PDT) to provide better outcomes with fewer side effects. Though significant development has been made in the field of phototherapeutic drugs, several challenges have restricted the use of PTT in clinical use and hence they have not yet been tested in large clinical trials. In this review, we attempted to discuss the progress, properties, applications, and challenges of 2D materials in the field of PTT and their application in photomedicine.

Indexed as

GraphiteNanostructuresNeoplasmsPhotochemotherapyHumansPhototherapyGraphiteboron nitridegraphenesmolybdenum disulfidephotothermal therapysolid tumor

Identifiers

PMID36753355
PMCPMC9975046

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.