Evidence map›Paper›PMID 36754934›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2023

Anti-inflammatory effect of biologic therapy in patients with psoriatic disease: A prospective cohort FDG PET study.

Kevin E Boczar, Rob S Beanlands, Steven J Glassman, Jerry Wang, Wanzhen Zeng, Robert A deKemp, Natalie C Ward, Christophe A Fehlmann, George A Wells, Jacob Karsh and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Coronary microvascular dysfunction in systemic inflammatory diseases: From pathophysiology and prevalence to diagnosis and management.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2025
    Review
  6. Molecular imaging of psoriatic arthritis.Current opinion in rheumatology · 2025
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Kevin E Boczar *University of Ottawa Heart Institute, Ottawa, ON, Canada.
Rob S Beanlands *University of Ottawa Heart Institute, Ottawa, ON, Canada.
Steven J GlassmanDivision of Dermatology, The Ottawa Hospital, Ottawa, ON, Canada.
Jerry WangUniversity of Ottawa Heart Institute, Ottawa, ON, Canada.
Wanzhen ZengUniversity of Ottawa Heart Institute, Ottawa, ON, Canada.
Robert A deKempUniversity of Ottawa Heart Institute, Ottawa, ON, Canada.
Natalie C WardSchool of Medicine, University of Western Australia, Perth, WA, Australia.
Christophe A FehlmannSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
George A WellsUniversity of Ottawa Heart Institute, Ottawa, ON, Canada.
Jacob Karsh *Division of Rheumatology, The Ottawa Hospital, Ottawa, ON, Canada.
Girish Dwivedi *University of Ottawa Heart Institute, Ottawa, ON, Canada. girish.dwivedi@perkins.uwa.edu.au.
University of Ottawa · CAOttawa Hospital · CAUniversity of Western Australia · AUOttawa Hospital Research InstituteUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of the study was to evaluate the changes in central vascular inflammation measured by FDG PET and myocardial blood flow reserve (MFR) determined by METHODS AND

resultsTarget-to-background ratio (TBR) by FDG PET in the most diseased segment of the ascending aorta (TBR

conclusionIn a cohort of psoriasis patients treated with biologics, FDG uptake in the thoracic aorta decreased over the study period. Patients who demonstrated a significant anti-inflammatory response on FDG PET imaging maintained their MFR compared to non-responders.

Indexed as

Arthritis, PsoriaticPsoriasisAnti-Inflammatory AgentsBiological FactorsFluorodeoxyglucose F18HumansInflammationPositron-Emission TomographyProspective StudiesAnti-Inflammatory AgentsBiological FactorsFluorodeoxyglucose F18cardiovascular diseaseinflammationPET imagingPsoriatic arthritis

Identifiers

PMID36754934
PMCPMC10372102
OpenAlexW4319454105

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.