Evidence map›Paper›PMID 36755307›Full record

ArticleGenetics2023

Xenbase: key features and resources of the Xenopus model organism knowledgebase.

Malcolm Fisher, Christina James-Zorn, Virgilio Ponferrada, Andrew J Bell, Nivitha Sundararaj, Erik Segerdell, Praneet Chaturvedi, Nadia Bayyari, Stanley Chu, Troy Pells and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 107 citations in OpenAlex.

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  14. Subcellular mass spectrometry reveals proteome remodeling in an asymmetrically dividing (frog) embryonic stem cell.Proceedings of the National Academy of Sciences of the United States of America · 2026
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Malcolm FisherXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0003-1074-8103
Christina James-ZornXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0001-5495-4588
Virgilio PonferradaXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-8590-7183
Andrew J BellXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-8828-8402
Nivitha SundararajXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-2278-0824
Erik SegerdellXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-9611-1279
Praneet ChaturvediXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-8713-6570
Nadia BayyariXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Stanley ChuXenbase, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.
Troy PellsXenbase, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-2340-5356
Vaneet LotayXenbase, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.
Sergei AgalakovXenbase, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.
Dong Zhuo WangXenbase, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.
Bradley I ArshinoffXenbase, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.
Saoirse FoleyDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA.ORCID 0000-0002-1791-2837
Kamran KarimiXenbase, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0001-5733-9409
Peter D VizeXenbase, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0001-8026-0424
Aaron M ZornXenbase, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0003-3217-3590
Cincinnati Children's Hospital Medical Center · USUniversity of Calgary · CACarnegie Mellon University · US

Funding

Xenbase: the Xenopus Model Organism KnowledgebaseP41HD064556 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI Aaron M Zorn · 2010 to 2026
$24.9M
NICHD NIH HHS P41 HD064556
6 · The paper itself

Abstract

Xenbase (https://www.xenbase.org/), the Xenopus model organism knowledgebase, is a web-accessible resource that integrates the diverse genomic and biological data from research on the laboratory frogs Xenopus laevis and Xenopus tropicalis. The goal of Xenbase is to accelerate discovery and empower Xenopus research, to enhance the impact of Xenopus research data, and to facilitate the dissemination of these data. Xenbase also enhances the value of Xenopus data through high-quality curation, data integration, providing bioinformatics tools optimized for Xenopus experiments, and linking Xenopus data to human data, and other model organisms. Xenbase also plays an indispensable role in making Xenopus data interoperable and accessible to the broader biomedical community in accordance with FAIR principles. Xenbase provides annotated data updates to organizations such as NCBI, UniProtKB, Ensembl, the Gene Ontology consortium, and most recently, the Alliance of Genomic Resources, a common clearing house for data from humans and model organisms. This article provides a brief overview of key and recently added features of Xenbase. New features include processing of Xenopus high-throughput sequencing data from the NCBI Gene Expression Omnibus; curation of anatomical, physiological, and expression phenotypes with the newly created Xenopus Phenotype Ontology; Xenopus Gene Ontology annotations; new anatomical drawings of the Normal Table of Xenopus development; and integration of the latest Xenopus laevis v10.1 genome annotations. Finally, we highlight areas for future development at Xenbase as we continue to support the Xenopus research community.

Indexed as

Databases, GeneticGenomicsAnimalsComputational BiologyHumansXenopusXenopus laevisgenomicsmodel organism databaseontologyXenbaseXenopus

Identifiers

PMID36755307
PMCPMC10158840
OpenAlexW4319655725

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.