Evidence map›Paper›PMID 36756499›Full record

ReviewNanoscale advances2023

Machine learning-augmented surface-enhanced spectroscopy toward next-generation molecular diagnostics.

Hong Zhou, Liangge Xu, Zhihao Ren, Jiaqi Zhu, Chengkuo Lee

Abstract readReview
In one paragraph

Review in Nanoscale advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
  2. Review
  3. Strategies for Multiplexing Plasmonic Biosensing.Sensors (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. AI-Guided SERS Defines a Pan-Cancer Diagnostic Biomarker.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hong ZhouDepartment of Electrical and Computer Engineering, National University of Singapore Singapore 117583 elelc@nus.edu.sg.ORCID https://orcid.org/0000-0002-3146-2238
Liangge XuDepartment of Electrical and Computer Engineering, National University of Singapore Singapore 117583 elelc@nus.edu.sg.ORCID https://orcid.org/0000-0002-2332-5321
Zhihao RenDepartment of Electrical and Computer Engineering, National University of Singapore Singapore 117583 elelc@nus.edu.sg.ORCID https://orcid.org/0000-0002-2520-0784
Jiaqi ZhuNational Key Laboratory of Special Environment Composite Technology, Harbin Institute of Technology Harbin 150001 China zhujq@hit.edu.cn.ORCID https://orcid.org/0000-0002-2142-7260
Chengkuo LeeDepartment of Electrical and Computer Engineering, National University of Singapore Singapore 117583 elelc@nus.edu.sg.ORCID https://orcid.org/0000-0002-8886-3649

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The world today is witnessing the significant role and huge demand for molecular detection and screening in healthcare and medical diagnosis, especially during the outbreak of COVID-19. Surface-enhanced spectroscopy techniques, including Surface-Enhanced Raman Scattering (SERS) and Infrared Absorption (SEIRA), provide lattice and molecular vibrational fingerprint information which is directly linked to the molecular constituents, chemical bonds, and configuration. These properties make them an unambiguous, nondestructive, and label-free toolkit for molecular diagnostics and screening. However, new issues in molecular diagnostics, such as increasing molecular species, faster spread of viruses, and higher requirements for detection accuracy and sensitivity, have brought great challenges to detection technology. Advancements in artificial intelligence and machine learning (ML) techniques show promising potential in empowering SERS and SEIRA with rapid analysis and automatic data processing to jointly tackle the challenge. This review introduces the combination of ML and SERS/SEIRA by investigating how ML algorithms can be beneficial to SERS/SEIRA, discussing the general process of combining ML and SEIRA/SERS, highlighting the molecular diagnostics and screening applications based on ML-combined SEIRA/SERS, and providing perspectives on the future development of ML-integrated SEIRA/SERS. In general, this review offers comprehensive knowledge about the recent advances and the future outlook regarding ML-integrated SEIRA/SERS for molecular diagnostics and screening.

Identifiers

PMID36756499
PMCPMC9890940

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.