Evidence map›Paper›PMID 36760567›Full record

ReviewFrontiers in cardiovascular medicine2023

Glycation of LDL: AGEs, impact on lipoprotein function, and involvement in atherosclerosis.

Anastasia V Poznyak, Vasily N Sukhorukov, Raisa Surkova, Nikolay A Orekhov, Alexander N Orekhov

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anastasia V PoznyakInstitute for Atherosclerosis Research, Moscow, Russia.
Vasily N SukhorukovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Raisa SurkovaLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Nikolay A OrekhovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Alexander N OrekhovInstitute for Atherosclerosis Research, Moscow, Russia.
Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RUInstitute for Atherosclerosis Research · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a complex disease, and there are many factors that influence its development and the course of the disease. A deep understanding of the pathological mechanisms underlying atherogenesis is needed to develop optimal therapeutic strategies and treatments. In this review, we have focused on low density lipoproteins. According to multiple studies, their atherogenic properties are associated with multiple modifications of lipid particles. One of these modifications is Glycation. We considered aspects related to the formation of modified particles, as well as the influence of modification on their functioning. We paid special attention to atherogenicity and the role of glycated low-density lipoprotein (LDL) in atherosclerosis.

Indexed as

AGEatherosclerosisglycationLDLLDL modificationlipids

Identifiers

PMID36760567
PMCPMC9904536
OpenAlexW4317907232

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.