Evidence map›Paper›PMID 36760593›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2023

Metabolic Characteristics of Gestational Diabetes Mellitus and the Effects on Pregnancy Outcomes.

Ping Luo, Ying Fan, Yusha Xiong, Chunlin Zhang, Zhiping Yang, Fenglan Sun, Bing Mei

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Management of gestational diabetes mellitusWorld journal of diabetes · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ping LuoDepartment of Laboratory Medicine, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, People's Republic of China.ORCID 0000-0002-0275-3706
Ying FanGongan County Maternal and Child Health Care Hospital, Jingzhou, People's Republic of China.ORCID 0000-0002-7064-0770
Yusha XiongGongan County Maternal and Child Health Care Hospital, Jingzhou, People's Republic of China.ORCID 0000-0003-4050-3262
Chunlin ZhangDepartment of Laboratory Medicine, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, People's Republic of China.ORCID 0000-0003-0425-3569
Zhiping YangDepartment of Laboratory Medicine, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, People's Republic of China.ORCID 0000-0001-8954-1732
Fenglan SunDepartment of Laboratory Medicine, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, People's Republic of China.ORCID 0000-0001-7751-7735
Bing MeiDepartment of Laboratory Medicine, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, People's Republic of China.ORCID 0000-0002-9332-3356
Yangtze University · CNJingzhou Maternal and Child Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To describe the metabolic characteristics of gestational diabetes mellitus (GDM) and assess their effects on perinatal outcomes. Methods: A two-center nested case‒control study was designed, including 192 pregnant women with GDM and 191 pregnant women with normal glucose tolerance (NGT). Serum glucose and insulin concentrations based upon the 75 g oral glucose tolerance test (OGTT) were measured. Several indices were calculated to describe the metabolic characteristics of the subjects. The relationship between glucose metabolism parameters and pregnancy outcomes was evaluated using stepwise linear regression and binary logistic regression. Results: Compared with the NGT group, the GDM group showed significantly higher fasting and postprandial glucose parameters but significantly lower fasting and postprandial insulin responses. Meanwhile, the GDM group had significantly lower HOMA-β, DI and ISI Conclusion: Beta cell dysfunction rather than insulin resistance determines the occurrence of GDM in the central Chinese population. Women with predominant insulin secretion defects had a similar risk of adverse perinatal outcomes to women with NGT. Our study provided a basis for the selection of glucose metabolism monitoring indicators useful for the prevention of adverse perinatal outcomes.

Indexed as

glucose metabolisminsulin resistanceinsulin sensitivityperinatal outcomestype 2 diabetes mellitus

Identifiers

PMID36760593
PMCPMC9843504
OpenAlexW4316590439

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.