Evidence mapPaperPMID 36762579Full record

SynthesisObesity (Silver Spring, Md.)2023

Sex differences in response to lifestyle intervention among children and adolescents: Systematic review and meta-analysis.

Alexis Mast, Armando Peña, Charlotte A Bolch, Gabriel Shaibi, Kiley B Vander Wyst

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Obesity (Silver Spring, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
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  5. Clinically effective child change in family-based behavioral treatment for pediatric obesity: An individual participant mega-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexis MastArizona College of Osteopathic Medicine, Midwestern University, Glendale, Arizona, USA.
Armando PeñaCenter for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA.
Charlotte A BolchOffice of Research and Sponsored Programs, Midwestern University, Glendale, Arizona, USA.ORCID 0000-0002-9797-6557
Gabriel ShaibiCenter for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation, Arizona State University, Phoenix, Arizona, USA.ORCID 0000-0002-6890-2903
Kiley B Vander WystCollege of Graduate Studies, Midwestern University, Glendale, Arizona, USA.ORCID 0000-0001-7182-4531

Funding

Multi-Level Effects of a Parenting Intervention for Enhancing Latino Youth Health BehaviorsU54MD002316 · NIMHD · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MARSIGLIA, FLAVIO FRANCISCO · 2017 to 2022
$14.9M
Urban American Indian Youth Substance Use: Ecodevelopmental Influences P20MD002316 · NIMHD · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MARSIGLIA, FLAVIO FRANCISCO · 2007 to 2016
$13.3M
Preventing Diabetes in Latino YouthR01DK107579 · NIDDK · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SHAIBI, GABRIEL QUANTUM · 2016 to 2025
$6.9M
Inflammatory mediators and beta-cell function among obese Latino youth with prediabetesF31DK125037 · NIDDK · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI PENA, ARMANDO · 2020 to 2021
$71k
NIDDK NIH HHS F31 DK125037NIDDK NIH HHS R01 DK107579NIMHD NIH HHS P20 MD002316NIMHD NIH HHS U54 MD002316
6 · The paper itself

Abstract

objectiveLittle is known about sex differences in response to lifestyle interventions among pediatric populations. The purpose of this analysis was to evaluate sex differences in adiposity following lifestyle interventions among children and adolescents with overweight or obesity aged 6 to 18 years old.

methodsSearches were conducted in PubMed, Web of Science, and MEDLINE (from inception to March 2021), and references from included articles were examined. Eligibility criteria included children and adolescents aged 6 to 18 years with overweight or obesity, randomization to a lifestyle intervention versus a control group, and assessment of at least one adiposity measure. Corresponding authors were contacted to obtain summary statistics by sex (n = 14/49).

resultsOf 89 full-text articles reviewed, 49 (55%) were included, of which 33 (67%) reported statistically significant intervention effects on adiposity. Only two studies (4%) evaluated sex differences in response to lifestyle intervention, reporting conflicting results. The results of the meta-regression models demonstrated no significant differences in the treatment effect between male and female youth for weight (beta = -0.05, SE = 0.18, z = -0.28, p = 0.8), BMI (beta = 0.03, SE = 0.14, z = 0.19, p = 0.85), BMI z score (beta = -0.04, SE = 0.18, z = -0.23, p = 0.82), percentage body fat (beta = -0.11, SE = 0.16, z = -0.67, p = 0.51), and waist circumference (beta = -0.30, SE = 0.25, z = -1.18, p = 0.24).

conclusionsThe meta-analysis revealed that youth with overweight or obesity do not demonstrate a differential response to lifestyle intervention in relation to adiposity-related outcomes.

Indexed as

OverweightPediatric ObesityAdiposityAdolescentBody Mass IndexChildFemaleHumansLife StyleMaleSex Characteristics

Identifiers

PMID36762579
PMCPMC10352023

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.