Evidence map›Paper›PMID 36763106›Full record

ArticleAnalytical and bioanalytical chemistry2023

Rapid evaluation of Radix Paeoniae Alba and its processed products by near-infrared spectroscopy combined with multivariate algorithms.

Jiuba Zhang, Yu Li, Bin Wang, Jiantao Song, Mingxuan Li, Peng Chen, Zheyuan Shen, Yi Wu, Chunqin Mao, Hui Cao and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jiuba Zhang *College of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Yu Li *College of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Bin WangCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Jiantao SongCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Mingxuan LiCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Peng ChenCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Zheyuan ShenCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Yi WuCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Chunqin MaoCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Hui CaoResearch Center for Traditional Chinese Medicine of Lingnan (Southern China), Jinan University, Guangzhou, 510632, China.
Xiachang WangCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China.
Wei ZhangCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China. zhangwei@ahtcm.edu.cn.
Tulin LuCollege of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023, People's Republic of China. ltl2021@njucm.edu.cn.

Funding

National Key R&D Program of China 2018YFC1707000National Key R&D Program of China 2019YFC1711500
6 · The paper itself

Abstract

It is well known that the processing method of herbal medicine has a complex impact on the active components and clinical efficacy, which is difficult to measure. As a representative herb medicine with diverse processing methods, Radix Paeoniae Alba (RPA) and its processed products differ greatly in clinical efficacy. However, in some cases, different processed products are confused for use in clinical practice. Therefore, it is necessary to strictly control the quality of RPA and its processed products. Giving that the time-consuming and laborious operation of traditional quality control methods, a comprehensive strategy of near-infrared (NIR) spectroscopy combined with multivariate algorithms was proposed. This strategy has the advantages of being rapid and non-destructive, not only qualitatively distinguishing RPA and various processed products but also enabling quantitative prediction of five bioactive components. Qualitatively, the subspace clustering algorithm successfully differentiated RPA and three processed products, with an accuracy rate of 97.1%; quantitatively, interval combination optimization (ICO), competitive adaptive reweighted sampling (CARS), and competitive adaptive reweighted sampling combined with successive projections algorithm (CARS-SPA) were used to optimize the PLS model, and satisfactory results were obtained in terms of wavelength selection. In conclusion, it is feasible to use NIR spectroscopy to rapidly evaluate the effect of processing methods on the quality of RPA, which provides a meaningful reference for quality control of other herbal medicines with numerous processing methods.

Indexed as

Drugs, Chinese HerbalPlants, MedicinalAlgorithmsHerbal MedicineLeast-Squares AnalysisPlant RootsSpectroscopy, Near-InfraredDrugs, Chinese HerbalMultivariate algorithmsNear-infrared spectroscopyRadix Paeoniae AlbaSubspace clusteringWavelength selection

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.