Evidence map›Paper›PMID 36763969›Full record

ReviewAnnual review of physiology2023

Flipping Off and On the Redox Switch in the Microcirculation.

Máté Katona, Mark T Gladwin, Adam C Straub

Open access · hybridAbstract readReview
In one paragraph

Review in Annual review of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Curcumin's Protective Effects Against HMolecules (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. A clinician's musings on oxygen: Too little or too much with life in the balance.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Máté KatonaPittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; email: astraub@pitt.edu.
Mark T GladwinPittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; email: astraub@pitt.edu.
Adam C StraubPittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; email: astraub@pitt.edu.
University of Pittsburgh · US

Funding

Vascular Subphenotypes of Lung DiseaseP01HL103455 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREEMAN, BRUCE ALAN · 2011 to 2020
$26.1M
Sickle Cell Disease and Cardiovascular Risk- Red Cell Exchange SCD-CARREUH3HL143192 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GLADWIN, MARK T · 2020 to 2025
$16.1M
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide HomeostasisR01HL098032 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin · 2009 to 2026
$12.5M
Antidote for inhaled CO poisoning based on mutationally engineered neuroglobinR01HL125886 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin, Jesus Tejero Bravo · 2015 to 2026
$7.9M
Basic and Translational Studies in Redox Regulation of Cardiovascular Physiology and DiseaseR35HL161177 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Adam Carl Straub · 2022 to 2026
$4.7M
Role of Xanthine Oxidase in Heme-induced Vascular DysfunctionR01HL153532 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KELLEY, ERIC EUGENE, STRAUB, ADAM CARL · 2021 to 2024
$2.1M
Type II Alveolar Redox Control in Fibrogenesis and ResolutionR01HL149825 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MORA, ANA LUCIA, STRAUB, ADAM CARL · 2020 to 2023
$2.1M
NHLBI NIH HHS P01 HL103455NHLBI NIH HHS R01 HL098032NHLBI NIH HHS R01 HL125886NHLBI NIH HHS R01 HL149825NHLBI NIH HHS R01 HL153532NHLBI NIH HHS R35 HL161177NHLBI NIH HHS UH3 HL143192
6 · The paper itself

Abstract

Resistance arteries and arterioles evolved as specialized blood vessels serving two important functions: (

Indexed as

VasoconstrictionVasodilationHumansMicrocirculationOxidation-ReductionOxygenOxygencalciumendothelialmicrocirculationred blood cellredoxsmooth muscle

Identifiers

PMID36763969
PMCPMC11046419
OpenAlexW4319881072

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.