Evidence mapPaperPMID 36764629Full record

ArticleMagnetic resonance imaging2023

Feasibility of joint mapping of triglyceride saturation and water longitudinal relaxation in a single breath hold applied to high fat-fraction adipose depots in the periclavicular anatomy.

Jason Ostenson, Ryan K Robison, Evan L Brittain, Bruce M Damon

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jason OstensonVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America; Dept. of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America. Electronic address: j.ostenson@vumc.org.
Ryan K RobisonVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America; Philips, Gainesville, FL, United States of America.
Evan L BrittainDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Bruce M DamonDept. of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America; Carle Clinical Imaging Research Program, Urbana, IL, United States of America; Stephens Family Clinical Research Institute, Carle Health, Urbana, IL, United States of America; Department of Bioengineering and Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, United States of America; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States of America.
Vanderbilt University Medical Center · USClinical Research Institute · US

Funding

Effect of PDE5 Inhibition on Adipose Metabolism in HumansR01DK124845 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · 2022 to 2025
$2.7M
Development and Application of Muscle Diffusion Tensor MRIR01AR073831 · NIAMS · CARLE FOUNDATION · PI BRUCE M. DAMON · 2023 to 2024
$759k
NIAMS NIH HHS R01 AR073831NIDDK NIH HHS R01 DK124845
6 · The paper itself

Abstract

introductionSimultaneous mapping of triglyceride (TAG) saturation and tissue water relaxation may improve the characterization of the structure and function of anatomies with significant adipose tissue. While several groups have demonstrated in vivo TAG saturation imaging using MRI, joint mapping of relaxation and TAG saturation is understudied. Such mappings may avoid bias from physiological motion, if they can be done within a single breath-hold, and also account for static and applied magnetic field heterogeneity.

methodsWe propose a transient-state/MR fingerprinting single breath-hold sequence at 3 T, a low-rank reconstruction, and a parameter estimation pipeline that jointly estimates the number of double bonds (NDB), number of methylene interrupted double bonds (NMIDB), and tissue water T

resultsThe simulation results demonstrate accurate NDB, NMIDB, and water T

conclusionRobust estimation of NDB, NMIDB at high FF and water T

Indexed as

Breath HoldingWaterAdipose TissueFeasibility StudiesHumansMagnetic Resonance ImagingObesityPhantoms, ImagingTriglyceridesTriglyceridesWaterAdipose tissueLongitudinal relaxationLow-rank reconstructionMagnetic resonance fingerprintingTriglyceride saturation

Identifiers

PMID36764629
PMCPMC10088071
OpenAlexW4319759093

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.