Evidence mapPaperPMID 36765154Full record

ArticleScientific reports2023

Prevalence and trends of perioperative major adverse cardiovascular and cerebrovascular events during cancer surgeries.

Venkataraghavan Ramamoorthy, Kelvin Chan, Sandeep Appunni, Zhenwei Zhang, Md Ashfaq Ahmed, Peter McGranaghan, Anshul Saxena, Muni Rubens

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Electrocardiographic characteristics of bladder cancer patients receiving preoperative chemotherapy combined with immunotherapy.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Venkataraghavan RamamoorthyMiami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Dr, Miami, FL, 33176, USA.
Kelvin ChanNova Southeastern University, Dr. Kiran C. Patel College of Allopathic Medicine, Davie, FL, USA.
Sandeep AppunniGovernment Medical College, Kozhikode, Kerala, India.
Zhenwei ZhangMiami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Dr, Miami, FL, 33176, USA.
Md Ashfaq AhmedMiami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Dr, Miami, FL, 33176, USA.
Peter McGranaghanDepartment of Internal Medicine and Cardiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität Zu Berlin, 10117, Berlin, Germany. peter.mcgranaghan@charite.de.
Anshul SaxenaMiami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Dr, Miami, FL, 33176, USA.
Muni RubensMiami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Dr, Miami, FL, 33176, USA. mrube001@fiu.edu.
Baptist Hospital of Miami · USGovernment Medical College · INHumboldt-Universität zu Berlin · DENova Southeastern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major adverse cardiovascular and cerebrovascular events (MACCE) is an important cause of morbidity and mortality during perioperative period. In this study, we looked for national trends in perioperative MACCE and its components as well as cancer types associated with high rates of perioperative MACCE during major cancer surgeries. This study was a retrospective analysis of the National Inpatient Sample, 2005-2014. Hospitalizations for surgeries of prostate, bladder, esophagus, pancreas, lung, liver, colorectal, and breast among patients 40 years and greater were included in the analysis. MACCE was defined as a composite measure that included in-hospital all-cause mortality, acute myocardial infarction (AMI), and ischemic stroke. A total of 2,854,810 hospitalizations for major surgeries were included in this study. Of these, 67,316 (2.4%) had perioperative MACCE. Trends of perioperative MACCE showed that it decreased significantly for AMI, death and any MACCE, while stroke did not significantly change during the study period. Logistic regression analysis for perioperative MACCE by cancer types showed that surgeries for esophagus, pancreas, lung, liver, and colorectal cancers had significantly greater odds for perioperative MACCE. The surgeries identified to have greater risks for MACCE in this study could be risk stratified for better informed decision-making and management.

Indexed as

Cerebrovascular DisordersMyocardial InfarctionNeoplasmsHumansLungMalePrevalenceRetrospective StudiesRisk Factors

Identifiers

PMID36765154
PMCPMC9918731
OpenAlexW4319922496

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.