Evidence map›Paper›PMID 36765341›Full record

ArticleBMC complementary medicine and therapies2023

In vitro antioxidant, anti-inflammatory, and anticancer activities of mixture Thai medicinal plants.

Suchada Jongrungraungchok, Fameera Madaka, Thaniya Wunnakup, Teeratad Sudsai, Chanamon Pongphaew, Thanapat Songsak, Nalinee Pradubyat

Abstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Phytosynbiotic Containing Double-Layer MicroencapsulatedAnimals : an open access journal from MDPI · 2026
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  6. Bioconversion ofCurrent issues in molecular biology · 2025
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  7. Article
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  9. Review
  10. Review
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  14. Review
  15. Evaluation ofFrontiers in chemistry · 2024
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suchada JongrungraungchokDepartment of Pharmaceutical Chemistry, College of Pharmacy, Rangsit University, Pathum Thani, 12000, Thailand.
Fameera MadakaDrug and Herbal Product Research and Development Center, College of Pharmacy, Rangsit University, Pathum Thani, 12000, Thailand.
Thaniya WunnakupDrug and Herbal Product Research and Development Center, College of Pharmacy, Rangsit University, Pathum Thani, 12000, Thailand.
Teeratad SudsaiDrug and Herbal Product Research and Development Center, College of Pharmacy, Rangsit University, Pathum Thani, 12000, Thailand.
Chanamon PongphaewPrincess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, 10210, Thailand.
Thanapat SongsakDepartment of Pharmacognosy, College of Pharmacy, Rangsit University, Pathum Thani, 12000, Thailand.
Nalinee PradubyatDepartment of Pharmacology, College of Pharmacy, Rangsit University, Pathum Thani, 12000, Thailand. nalinee.p@rsu.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe phytochemical study of medicinal plants is rapidly gaining popularity with many pharmacologic effects. This study aims to determine the antioxidant capacity as well as anticancer and antimigration activities of Clear belongs Plus extract (CBL-P) which consisted of five medicinal plants namely, Alpinia galanga, Piper nigrum, Citrus aurantifolia, Tiliacora triandra, and Cannabis sativa on human colon cancer cells SW620 and HCT116 cell lines, and human non-small cell lung cancer cells A549 and NCI-H460 cell lines.

methodsIn this study the dried-plant powder was extracted using 90% ethanol. Additionally, CBL-P was studied antioxidative activity via DPPH and ABTS assays and anti-inflammatory activities using nitric oxide assay using Griess reaction. Antiproliferation and antimigration of CBL-P were investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) and scratch assay.

resultsThe results showed that CBL-P had potent antiproliferative activity with IC

conclusionIn conclusion, the mixture extract possessed antioxidant and anti-inflammatory activity. Furthermore, the mixture plant extract significantly exhibited antiproliferative and antimigration activities on SW620, HCT116, A549, and NCI-H460 cells (P ≤ 0.05). Taken together, our results suggest that medicinal plants may have synergistic effects that could potentially enhance the effectiveness of cancer treatment when used as adjuvants. These findings provide a solid scientific foundation for future efforts to explore the mechanism of action.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsPlant ExtractsPlants, MedicinalAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsBenzothiazolesCell Line, TumorHumansNitric OxideSulfonic Acids2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsBenzothiazolesNitric OxidePlant ExtractsSulfonic AcidsAlpinia galangaAntimigrationAntiproliferative activityCannabis sativaCitrus aurantifoliaPiper nigrumTiliacora triandra

Identifiers

PMID36765341
PMCPMC9912591

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.