Evidence map›Paper›PMID 36766543›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Cardiovascular Involvement in Tuberculosis: From Pathophysiology to Diagnosis and Complications-A Narrative Review.

Dragos Traian Marius Marcu, Cristina Andreea Adam, Florin Mitu, Carmen Cumpat, Viviana Aursulesei Onofrei, Mihai Lucian Zabara, Alexandru Burlacu, Radu Crisan Dabija

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Healthcare Costs and Trends of Multimorbidity in COPD Patients: A Population-Based Study in Singapore.International journal of chronic obstructive pulmonary disease · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Cardiovascular Complications from Tuberculosis.Reviews in cardiovascular medicine · 2025
    Review
  16. Article
  17. The great masquerade: TB endomyocarditis as left ventricular mass.Indian journal of thoracic and cardiovascular surgery · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dragos Traian Marius MarcuDepartment of Medical Specialties (I and III) and Surgical Specialties, Grigore T. Popa University of Medicine and Pharmacy, University Street No. 16, 700115 Iaşi, Romania.ORCID 0000-0003-2334-9953
Cristina Andreea AdamDepartment of Medical Specialties (I and III) and Surgical Specialties, Grigore T. Popa University of Medicine and Pharmacy, University Street No. 16, 700115 Iaşi, Romania.ORCID 0000-0001-7313-3320
Florin MituDepartment of Medical Specialties (I and III) and Surgical Specialties, Grigore T. Popa University of Medicine and Pharmacy, University Street No. 16, 700115 Iaşi, Romania.ORCID 0000-0003-1801-9327
Carmen CumpatClinical Rehabilitation Hospital, Cardiovascular Rehabilitation Clinic, Pantelimon Halipa Street No. 14, 700661 Iasi, Romania.
Viviana Aursulesei OnofreiDepartment of Medical Specialties (I and III) and Surgical Specialties, Grigore T. Popa University of Medicine and Pharmacy, University Street No. 16, 700115 Iaşi, Romania.
Mihai Lucian ZabaraDepartment of Medical Specialties (I and III) and Surgical Specialties, Grigore T. Popa University of Medicine and Pharmacy, University Street No. 16, 700115 Iaşi, Romania.
Alexandru BurlacuDepartment of Medical Specialties (I and III) and Surgical Specialties, Grigore T. Popa University of Medicine and Pharmacy, University Street No. 16, 700115 Iaşi, Romania.ORCID 0000-0002-3424-1588
Radu Crisan DabijaDepartment of Medical Specialties (I and III) and Surgical Specialties, Grigore T. Popa University of Medicine and Pharmacy, University Street No. 16, 700115 Iaşi, Romania.ORCID 0000-0003-3732-0350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although primarily a lung disease, extra-pulmonary tuberculosis (TB) can affect any organ or system. Of these, cardiovascular complications associated with disease or drug toxicity significantly worsen the prognosis. Approximately 60% of patients with TB have a cardiovascular disease, the most common associated pathological entities being pericarditis, myocarditis, and coronary artery disease. We searched the electronic databases PubMed, MEDLINE, and EMBASE for studies that evaluated the impact of TB on the cardiovascular system, from pathophysiological mechanisms to clinical and paraclinical diagnosis of cardiovascular involvement as well as the management of cardiotoxicity associated with antituberculosis medication. The occurrence of pericarditis in all its forms and the possibility of developing constrictive pericarditis, the association of concomitant myocarditis with severe systolic dysfunction and complication with acute heart failure phenomena, and the long-term development of aortic aneurysms with risk of complications, as well as drug-induced toxicity, pose complex additional problems in the management of patients with TB. In the era of multidisciplinarity and polymedication, evidence-based medicine provides various tools that facilitate an integrative management that allows early diagnosis and treatment of cardiac pathologies associated with TB.

Indexed as

aortitiscardiotoxicitycardiovascular involvementmyocarditispericarditistuberculosis

Identifiers

PMID36766543
PMCPMC9914020

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.