Evidence map›Paper›PMID 36768216›Full record

ArticleInternational journal of molecular sciences2023

Organogermanium THGP Induces Differentiation into M1 Macrophages and Suppresses the Proliferation of Melanoma Cells via Phagocytosis.

Junya Azumi, Tomoya Takeda, Yasuhiro Shimada, Tao Zhuang, Yoshihiko Tokuji, Naoya Sakamoto, Hisashi Aso, Takashi Nakamura

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Immunomodulation of Skin Cancer.International journal of molecular sciences · 2023
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Junya AzumiResearch Division, Asai Germanium Research Institute Co., Ltd., Suzuranoka 3-131, Hakodate 042-0958, Japan.ORCID 0000-0003-2902-1561
Tomoya TakedaResearch Division, Asai Germanium Research Institute Co., Ltd., Suzuranoka 3-131, Hakodate 042-0958, Japan.
Yasuhiro ShimadaResearch Division, Asai Germanium Research Institute Co., Ltd., Suzuranoka 3-131, Hakodate 042-0958, Japan.
Tao ZhuangLaboratory of Animal Health Science, Graduate School of Agricultural Science, Tohoku University, 468-1 Aoba, Aramaki, Aoba-ku, Sendai 980-8572, Japan.ORCID 0000-0003-1475-7138
Yoshihiko TokujiDepartment of Human Sciences, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2 Sen, Inada, Obihiro 080-8555, Japan.ORCID 0000-0001-6476-3363
Naoya SakamotoIsotope Imaging Laboratory, Creative Research Institution, Hokkaido University, Kita 10 Jo-Nishi 5, Kita, Sapporo 060-0810, Japan.
Hisashi AsoLaboratory of Animal Health Science, Graduate School of Agricultural Science, Tohoku University, 468-1 Aoba, Aramaki, Aoba-ku, Sendai 980-8572, Japan.
Takashi NakamuraResearch Division, Asai Germanium Research Institute Co., Ltd., Suzuranoka 3-131, Hakodate 042-0958, Japan.ORCID 0000-0003-4625-9416

Funding

Asai Germanium Research Institute Nothing
6 · The paper itself

Abstract

M1 macrophages are an important cell type related to tumor immunology and are known to phagocytose cancer cells. In previous studies, the organogermanium compound poly-

Indexed as

MacrophagesMelanoma, ExperimentalAnimalsCell DifferentiationMicePhagocytosisRAW 264.7 CellsGe-132M1 macrophagemelanomaorganogermaniumTHGP

Identifiers

PMID36768216
PMCPMC9915250

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.